Active Recombinant Mouse IL1RL1, HIgG1 Fc-tagged
Cat.No. : | IL1RL1-505H |
Product Overview : | The extracellular domain of human IL-33R[ST2] (AAH30975.1) (Lys19-Phe328) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
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- Gene Information
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Description : | The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene inmouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the functionof helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) andinterleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome2q12. Alternative splicing of this gene results in multiple transcript variants |
Source : | CHO cell |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to bind Recombinant Human IL‑33 in a functional ELISA. |
Molecular Mass : | 61KDa (monomer) |
AA Sequence : | Lys19-Phe328 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | IL1RL1 interleukin 1 receptor-like 1 [ Homo sapiens ] |
Official Symbol : | IL1RL1 |
Synonyms : | IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623; |
Gene ID : | 9173 |
mRNA Refseq : | NM_003856 |
Protein Refseq : | NP_003847 |
MIM : | 601203 |
UniProt ID : | Q01638 |
Chromosome Location : | 2q12 |
Function : | cytokine receptor activity; interleukin-1 receptor activity; interleukin-33 binding; protein binding; receptor activity; receptor signaling protein activity; |
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◆ Lysates | ||
IL1RL1-001MCL | Recombinant Mouse IL1RL1 cell lysate | +Inquiry |
IL1RL1-1883HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
IL1RL1-2481HCL | Recombinant Human IL1RL1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL1RL1 has multiple splice variants that differ in signaling capabilities.
IL1RL1 suppresses allergic responses by inhibiting mast cell activation.
IL1RL1 is implicated in rheumatoid arthritis.
IL1RL1 increases the production of IL-4 and IL-13.
IL1RL1 is primarily membrane-bound.
IL1RL1 promotes Th2 cell differentiation.
IL1RL1 binds to IL-33 and IL-36 to initiate signaling.
IL1RL1 expression is altered in lung and breast cancer.
IL1RL1 undergoes glycosylation and phosphorylation.
IL1RL1 expression is upregulated in asthmatic conditions.
Customer Reviews (3)
Write a reviewHigh specificity in ELISA.
Suitable for flow cytometry.
Effective in allergy models.
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