Active Recombinant Mouse IL1RL1, MIgG2a Fc-tagged

• Cat.No.: IL1RL1-503M
• Product Overview: The extracellular domain of mouse IL-33R[ST2] (NP_001020773.1) (Ser27-Ser342) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Protein Length: 27-342 a.a.
• Description: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene inmouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the functionof helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) andinterleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome2q12. Alternative splicing of this gene results in multiple transcript variants
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to bind Recombinant Mouse IL‑33 in a functional ELISA.
• Molecular Mass: 63KDa (monomer)
• AA Sequence: Ser27-Ser342)
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: >98%, by SDS-PAGE under reducing conditions
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Il1rl1 interleukin 1 receptor-like 1 [ Mus musculus ]
• Official Symbol: IL1RL1
• Synonyms: IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; T1; protein T1; lymphocyte antigen 84; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
• Gene ID: 17082
• mRNA Refseq: NM_001025602
• Protein Refseq: NP_001020773
• Function: interleukin-1 receptor activity; interleukin-33 binding; interleukin-33 receptor activity; receptor activity; transmembrane signaling receptor activity