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  • Official Full Name

    interleukin 31 receptor A

  • Overview

    The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
  • Synonyms

    IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; sol;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • E.coli
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • hFc
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • human|IgG1|Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL31RA-732H Active Recombinant Human IL31RA protein, His-tagged HEK293 His Met1-Ser516
Human IL31RA-1350H Acitve Recombinant Human IL31RA protein(Met1-Ser516), hFc-tagged HEK293 C-hFc Met1-Ser516
Human IL31RA-731H Recombinant Human IL31RA protein, Fc-tagged HEK293 human/IgG1/Fc Ala20-Glu519
Human IL31RA-1318H Recombinant Human IL31RA protein, His & T7-tagged E.coli His/T7 Val205~Gly456 (Accession # Q8NI17)
Human IL31RA-854HCL Recombinant Human IL31RA cell lysate N/A
Human IL31RA-3594H Recombinant Human IL31RA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL31RA-1920H Recombinant Human IL31RA Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IL31RA-5191H Recombinant Human IL31RA Protein, GST-tagged Wheat Germ GST
Human IL31RA-2933H Recombinant Human IL31RA Protein (Val130-Asp622), N-His tagged E.coli N-His Val130-Asp622
Human IL31RA-2312H Recombinant Human IL31RA Protein, His-tagged E.coli N-His Ala20-Glu519
Human IL31RA-5777HF Recombinant Full Length Human IL31RA Protein, GST-tagged In Vitro Cell Free System GST 732 amino acids
Human IL31RA-151H Recombinant Human IL31RA Protein, His-tagged Human Cells His
Human IL31RA-1012H Active Recombinant Human IL31RA protein, His-tagged HEK293 His Ala20-Glu519
Human IL31RA-2934H Recombinant Human IL31RA Protein (Val20-Asp512), His tagged E.coli His Val20-Asp512
Human IL31RA-0277H Active Recombinant Human IL31RA protein, Fc-tagged HEK293 Fc Ala20-Glu519
Mouse IL31RA-8168M Recombinant Mouse IL31RA Protein Mammalian Cell His
Mouse IL31RA-4515M Recombinant Mouse IL31RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IL31RA-4515M-B Recombinant Mouse IL31RA Protein Pre-coupled Magnetic Beads HEK293
Mouse Il31ra-3520M Recombinant Mouse Il31ra Protein, Myc/DDK-tagged HEK293T Myc/DDK
E.coli IL31RA-2630M Recombinant Mouse IL31RA Protein (19-499 aa), His-tagged E.coli His 19-499 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL31RA Related Gene Family
  • IL31RA Related Research Area

IL31RA involved in several pathways and played different roles in them. We selected most pathways IL31RA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL31RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IL31RA has several biochemical functions, for example, cytokine binding, cytokine receptor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL31RA itself. We selected most functions IL31RA had, and list some proteins which have the same functions with IL31RA. You can find most of the proteins on our site.

Function Related Protein
cytokine bindingKITB;Fzd4;CRLF1;PARK7;LIFR;GBP1;IL31RA;TNFRSF11A;CD74
cytokine receptor activityIL17RB;LIFRB;IL13RA1;IL20RA;IL21R.2;IRX1;CRFB6;IL2RGA;IL12RB2
protein kinase bindingEPHA1;FGF19;CCNL2;C10orf46;NR4A3;SLC12A4;GCSAM;RAB8A;TRAF6
transcription coactivator activityRB1;ENY2;KDM5A;MNT;TDRD3;NEUROG3;LPIN2;PQBP1;RUNX1

IL31RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL31RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL31RA.


  • Q&As
  • Reviews

Q&As (6)

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Can recombinant IL31RA treat eczema? 12/03/2022

Recombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.

How is the research progress of IL31RA? 09/09/2022

The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.

Is recombinant IL31RA associated with chronic diseases? 06/30/2021

IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.

What are the clinical applications of IL31RA? 08/11/2020

The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.

Does IL31RA have serious side effects? 03/14/2020

The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.

What is the relationship between IL31RA and immune response? 04/08/2019

This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.

Customer Reviews (3)

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    Sensitivity and accuracy of the experiment were significantly improved by using this protein.


      The synthesis process is efficient and reliable, reducing experimental time and cost.


        Good stability and is suitable for long-term storage and use.

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