IL31RA
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Official Full Name
interleukin 31 receptor A
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Background
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. -
Synonyms
IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; sol;
- Involved Pathway
- Protein Function
- Interacting Protein
- IL31RA Related Gene Family
- IL31RA Related Research Area
IL31RA involved in several pathways and played different roles in them. We selected most pathways IL31RA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL31RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
IL31RA has several biochemical functions, for example, cytokine binding, cytokine receptor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL31RA itself. We selected most functions IL31RA had, and list some proteins which have the same functions with IL31RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine binding | CRLF1;GBP1;NRP2;CSF1R;CD74;CSF1RA;IFNGR1;ELANE;LIFR |
| cytokine receptor activity | CRFB4;PRLRA;LIFRB;IL15RA;F3;IL11RA;Ifnlr1;CRFB6;F3A |
| protein kinase binding | CAMK2N2;HDAC7;NBEA;RHEB;AKAP1;NPM1;KIF11;PRKCZ;PDGFRB |
| transcription coactivator activity | MTF1;JUND;NEUROD1;PER2;RNF20;GTF2F1;TAF11;RAN;RNF14 |
IL31RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL31RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL31RA.
TXNL4A
- Q&As
- Reviews
Q&As (6)
Ask a questionRecombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.
The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.
IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.
The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.
The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.
This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.
Customer Reviews (3)
Write a reviewThis protein has the characteristics of high purity, high expression, biological activity and functional stability in production -
IL-31RA has good structural stability under suitable storage conditions and can maintain its structural integrity and functional activity, which is very important for preservation and stability during production and use. -
Efficient expression systems have been developed that are capable of generating large amounts of IL-31RA in mass production to meet clinical needs. -
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