• Official Full Name

    interleukin 31 receptor A

  • Background

    The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
  • Synonyms

    IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; sol;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • E.coli
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • His (Fc)
    • Avi
    • His|T7
    • human|IgG1|Fc
    • Myc
    • DDK
    • Myc|DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    E.coli IL31RA-2630M Recombinant Mouse IL31RA Protein (19-499 aa), His-tagged E.coli His
    Human IL31RA-1920H Recombinant Human IL31RA Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IL31RA-1318H Recombinant Human IL31RA protein, His & T7-tagged E.coli His/T7
    Human IL31RA-854HCL Recombinant Human IL31RA cell lysate N/A
    Human IL31RA-3594H Recombinant Human IL31RA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL31RA-731H Recombinant Human IL31RA protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL31RA-5191H Recombinant Human IL31RA Protein, GST-tagged Wheat Germ GST
    Human IL31RA-2312H Recombinant Human IL31RA Protein, His-tagged E.coli N-His
    Human IL31RA-151H Recombinant Human IL31RA Protein, His-tagged Human Cells His
    Human IL31RA-1012H Recombinant Human IL31RA protein, His-tagged HEK293 His
    Human IL31RA-0277H Recombinant Human IL31RA protein, Fc-tagged HEK293 Fc
    Human IL31RA-732H Recombinant Human IL31RA protein, His-tagged HEK293 His
    Mouse IL31RA-4515M Recombinant Mouse IL31RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse IL31RA-4515M-B Recombinant Mouse IL31RA Protein Pre-coupled Magnetic Beads HEK293
    Mouse Il31ra-3520M Recombinant Mouse Il31ra Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse IL31RA-8168M Recombinant Mouse IL31RA Protein Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL31RA Related Gene Family
    • IL31RA Related Research Area

    IL31RA involved in several pathways and played different roles in them. We selected most pathways IL31RA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL31RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    IL31RA has several biochemical functions, for example, cytokine binding, cytokine receptor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL31RA itself. We selected most functions IL31RA had, and list some proteins which have the same functions with IL31RA. You can find most of the proteins on our site.

    Function Related Protein
    cytokine bindingCRLF1;GBP1;NRP2;CSF1R;CD74;CSF1RA;IFNGR1;ELANE;LIFR
    cytokine receptor activityCRFB4;PRLRA;LIFRB;IL15RA;F3;IL11RA;Ifnlr1;CRFB6;F3A
    protein kinase bindingCAMK2N2;HDAC7;NBEA;RHEB;AKAP1;NPM1;KIF11;PRKCZ;PDGFRB
    transcription coactivator activityMTF1;JUND;NEUROD1;PER2;RNF20;GTF2F1;TAF11;RAN;RNF14

    IL31RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL31RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL31RA.


    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Can recombinant IL31RA treat eczema? 12/03/2022

    Recombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.

    How is the research progress of IL31RA? 09/09/2022

    The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.

    Is recombinant IL31RA associated with chronic diseases? 06/30/2021

    IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.

    What are the clinical applications of IL31RA? 08/11/2020

    The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.

    Does IL31RA have serious side effects? 03/14/2020

    The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.

    What is the relationship between IL31RA and immune response? 04/08/2019

    This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.

    Customer Reviews (3)

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      This protein has the characteristics of high purity, high expression, biological activity and functional stability in production -


        IL-31RA has good structural stability under suitable storage conditions and can maintain its structural integrity and functional activity, which is very important for preservation and stability during production and use. -


          Efficient expression systems have been developed that are capable of generating large amounts of IL-31RA in mass production to meet clinical needs. -

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