Recombinant Human IL31RA Protein, His-tagged

• Cat.No.: IL31RA-2312H
• Product Overview: Recombinant Human IL31RA Protein (Ala20-Glu519) with a N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 60.7 kDa
  Accurate Molecular Mass: 63 kDa
• Protein length: Ala20-Glu519
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: IL31RA interleukin 31 receptor A [ Homo sapiens (human) ]
• Official Symbol: IL31RA
• Synonyms: IL31RA; interleukin 31 receptor A; interleukin-31 receptor subunit alpha; CRL; CRL3; GLM R; Glmr; IL 31RA; zcytoR17; IL-31R subunit alpha; cytokine receptor-like 3; class I cytokine receptor; IL-31 receptor subunit alpha; gp130-like monocyte receptor; soluble type I cytokine receptor CRL3; GPL; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384; MGC125346
• Gene ID: 133396
• mRNA Refseq: NM_001242636
• Protein Refseq: NP_001229565
• MIM: 609510
• UniProt ID: Q8NI17