Recombinant Mouse Il31ra Protein, Myc/DDK-tagged

Cat.No. : Il31ra-3520M
Product Overview : Purified recombinant protein of mouse full-length interleukin 31 receptor A (cDNA clone MGC:76531 IMAGE:30475340), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 56.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Il31ra interleukin 31 receptor A [ Mus musculus (house mouse) ]
Official Symbol : Il31ra
Synonyms : Il31ra; interleukin 31 receptor A; G; GLM; GPL; CRL3; Glmr; NR10; GLM-R; interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; class I cytokine receptor; cytokine receptor NR10; gp130-like monocyte receptor; gp130-like receptor; interleukin 31RA; interleukin-31 receptor subunit alpha short peptide; mGLM-R; novel cytokine receptor 10; zcytoR17
Gene ID : 218624
mRNA Refseq : NM_139299
Protein Refseq : NP_647460
UniProt ID : Q8K5B1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (6)

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Can recombinant IL31RA treat eczema? 12/03/2022

Recombinant IL31RA is promising as a potential treatment for eczema, but further research and clinical trials are needed to confirm its efficacy.

How is the research progress of IL31RA? 09/09/2022

The research of IL31RA is ongoing, and there are some relevant research results, but more experiments are needed to confirm its mechanism of action and clinical application.

Is recombinant IL31RA associated with chronic diseases? 06/30/2021

IL31RA is associated with some chronic diseases, such as asthma and eczema, but the specific mechanism still needs to be further studied.

What are the clinical applications of IL31RA? 08/11/2020

The IL31RA can be used in drug development, possibly in the treatment of allergic diseases, skin inflammation and pain.

Does IL31RA have serious side effects? 03/14/2020

The current research on the side effects of IL31RA is not perfect, but there may be local injection site reactions, mild allergic reactions and other situations.

What is the relationship between IL31RA and immune response? 04/08/2019

This protein is involved in the regulation of immune response and may play an important regulatory role in allergic diseases.

Customer Reviews (3)

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    Sensitivity and accuracy of the experiment were significantly improved by using this protein.


      The synthesis process is efficient and reliable, reducing experimental time and cost.


        Good stability and is suitable for long-term storage and use.

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