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KAT6A

  • Official Full Name

    K(lysine) acetyltransferase 6A

  • Overview

    MYST histone acetyltransferase (monocytic leukemia) 3, also known as MYST3, is an enzyme that, in humans, is encoded by the MYST3 gene.
  • Synonyms

    KAT6A; K(lysine) acetyltransferase 6A; RUNXBP2; MOZ; Monocytic leukemia zinc finger protein; ZNF220; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; KAT6A; EC 2.3.1.48; runt-related transcription factor binding protein 2; MGC167033; Runt-related transcription factor-binding protein 2; Zinc finger protein 220; EC 3.1.26.4; MYST3; histone acetyltransferase MYST3; MYST-3; OTTHUMP00000197392; OTTHUMP00000197394; OTTHUMP00000225722; MYST histone acetyltransferase (monocytic leukemia) 3;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Zebrafish
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N
  • FLAG
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KAT6A-5866H Recombinant Human KAT6A Protein, GST-tagged Wheat Germ GST
Human KAT6A-12H Recombinant Human KAT6A Protein (488-778), N-hFc tagged Insect Cell N-FLAG 488-778
Rat KAT6A-3156R Recombinant Rat KAT6A Protein Mammalian Cell His
Rat KAT6A-2812R Recombinant Rat KAT6A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KAT6A-2812R-B Recombinant Rat KAT6A Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KAT6A-6689Z Recombinant Zebrafish KAT6A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KAT6A Related Articles
  • KAT6A Related Research Area

KAT6A involved in several pathways and played different roles in them. We selected most pathways KAT6A participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesKAT6A;RBBP4;C3orf75;SAP130;KIAA1267;SMARCE1;MSL1;EED;KDM5C
Chromatin organizationKDM5C;ATXN7L3;DMAP1;EP400;ATF7IP;PHF17;C3orf75;C17orf81;KDM5BB
HATs acetylate histonesMCRS1;BRPF3;ING5A;DMAP1;ING5B;ING5;TADA2A;KIAA1267;SAP130

KAT6A has several biochemical functions, for example, DNA binding, histone acetyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT6A itself. We selected most functions KAT6A had, and list some proteins which have the same functions with KAT6A. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZFP422;LZTS1;CXXC1B;ZNF524;IER2;ZNF521;ATOH8;SS18L1;HIST1H2BL
histone acetyltransferase activityKAT2B;KAT7;TAF1L;HAT1;KAT6A;CREBBP;KAT8;KAT7A;METTL8
metal ion bindingHEPHL1A;MICAL2;ATP1A2A;GNAT1;CTDSPL;VDRB;ZNF501;ZFP821;ZNF680
transcription coactivator activityJUNBB;TAF10;MYOCD;ABT1;LPIN1;ZEB1;PCBD1;ESR2;DDX5
transferase activityMAPKAPK2B;TOMT;ELOVL7A;MAP2K4A;FUT9B;UGT5E1;ELOVL3;NLK1;ZDHHC16B
transferase activity, transferring acyl groups other than amino-acyl groupsSCP2A;KAT7A;KAT6A;HTATIP;ELOVL6;ACAA1A;DGAT2L6;MOGAT3A;KAT7B
zinc ion bindingTHRA;S100A8;TCEA2;SEC24C;TRIM39;ZNF212;ESRRGB;RNF144B;DBF4

KAT6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT6A here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT6A.

Arboleda, VA; Lee, H; et al. De Novo Nonsense Mutations in KAT6A, a Lysine Acetyl-Transferase Gene, Cause a Syndrome Including Microcephaly and Global Developmental Delay. AMERICAN JOURNAL OF HUMAN GENETICS 96:498-506(2015).
Tham, E; Lindstrand, A; et al. Dominant Mutations in KAT6A Cause Intellectual Disability with Recognizable Syndromic Features. AMERICAN JOURNAL OF HUMAN GENETICS 96:507-513(2015).
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