Recombinant Human KAT6A Protein, GST-tagged

• Cat.No.: KAT6A-5866H
• Product Overview: Human MYST3 partial ORF ( NP_006757, 81 a.a. - 179 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.63 kDa
• AA Sequence: ALPKPRNHGKLDNKQNVDWNKLIKR AVEGLAESGGSTLKSIERFLKGQKD VSALFGGSAASGFHQQLRLAIKRAI GHGRLLKDGPLYRLNTKATNVDGK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KAT6A lysine acetyltransferase 6A [ Homo sapiens (human) ]
• Official Symbol: KAT6A
• Synonyms: KAT6A; lysine acetyltransferase 6A; MOZ; MRD32; MYST3; MYST-3; ZNF220; RUNXBP2; ZC2HC6A; histone acetyltransferase KAT6A; K(lysine) acetyltransferase 6A; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; histone acetyltransferase MYST3; monocytic leukemia zinc finger protein; runt-related transcription factor binding protein 2; zinc finger protein 220; EC 2.3.1.48
• Gene ID: 7994
• mRNA Refseq: NM_001305878
• Protein Refseq: NP_001292807
• MIM: 601408
• UniProt ID: Q92794