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Official Full Name Kruppel-like factor 1 (erythroid)
Background This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
Synonyms KLF1; Kruppel-like factor 1 (erythroid); Krueppel-like factor 1; EKLF; erythroid Kruppel like factor; monoclonal A3D8; erythroid Kruppel-like factor; erythroid krueppel-like transcription factor; erythroid-specific transcription factor EKLF; INLU; HBFQT
    • Species :
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His-B2M
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KLF1-394H Recombinant Human KLF1, GST-tagged E.coli GST
    Human KLF1-395H Recombinant Human KLF1 protein, His-B2M-tagged E. coli His-B2M
    Rhesus Macaque KLF1-2411R Recombinant Rhesus monkey KLF1 Protein, His-tagged Mammalian Cell His
    Zebrafish KLF1-8577Z Recombinant Zebrafish KLF1 Mammalian Cell His

    klf1 involved in several pathways and played different roles in them. We selected most pathways klf1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with klf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    klf1 has several biochemical functions, for example, core promoter proximal region sequence-specific DNA binding, metal ion binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by klf1 itself. We selected most functions klf1 had, and list some proteins which have the same functions with klf1. You can find most of the proteins on our site.

    Function Related Protein
    core promoter proximal region sequence-specific DNA binding DMRTA2; SP3A; DMRT2A; SMAD3; DMRTA1; UHRF1; SP3; DMRT3; DMRT3A; DMRTC2
    metal ion binding NR1D2A; SUMF2; OGDH; CYP46A1.4; A3GALT2; GALNT7; ZNF711; CYP2K6; CDK2; NUDT13
    transcription factor activity, sequence-specific DNA binding HMGB1; TTC4; MZF1; ZNF436; RORAB; PHF5A; GAS7; DMRTC1B; ZNF498; SCAND1
    transcription regulatory region DNA binding BCL11B; IKZF3; ETV5; ZBTB14; ZFP161; ZFP382; TAF2; HIVEP2A; SOX2; DLX5

    klf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with klf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of klf1.


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