KRT18

  • Official Full Name

    keratin 18

  • Background

    KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    KRT18; keratin 18; K18; CYK18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein;
    • Type:
    • Native Proteins
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Human
    • Mouse
    • Pig
    • Rat
    • Zebrafish
    • Source :
    • bovine liver
    • E. coli
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • His|T7
    • N/A
    • N
    • T7|His|TEV cleavage site
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine KRT18-173B Native bovine KRT18 bovine liver N/A
    Human KRT18-12H Recombinant Human KRT18 protein, His-tagged E.coli His
    Human KRT18-266H Recombinant Human Cytokeratin-18 , His-tagged E.coli His
    Human KRT18-174H Recombinant Human KRT18 Protein, His-tagged E.coli His
    Human KRT18-464H Recombinant Human Keratin 18 E.coli N/A
    Human KRT18-13H Recombinant Human KRT18 protein, T7/His-tagged E.coli T7/His/TEV cleavage site
    Human KRT18-27702TH Recombinant Human KRT18, His-tagged E.coli His
    Human KRT18-4877HCL Recombinant Human KRT18 293 Cell Lysate HEK293 N/A
    Human KRT18-4876HCL Recombinant Human KRT18 293 Cell Lysate HEK293 N/A
    Human KRT18-487H Recombinant Human KRT18 protein, GST-tagged E. coli GST
    Human KRT18-4867H Recombinant Human KRT18 Protein, GST-tagged Wheat Germ GST
    Human KRT18-4348H Recombinant Human KRT18 protein, His-tagged Insect Cell His
    Human KRT18-3146H Recombinant Human KRT18 protein, His-tagged E.coli His
    Human KRT18-5030H Recombinant Human KRT18 protein, His-tagged HEK293 His
    Human KRT18-3148H Recombinant Human KRT18 protein E.coli N/A
    Human KRT18-3147H Recombinant Human KRT18 protein, His-tagged E.coli His
    Human KRT18-1075H Recombinant Human KRT18 Protein, His-tagged E.coli N-His
    Human KRT18-5928HF Recombinant Full Length Human KRT18 Protein, GST-tagged In Vitro Cell Free System GST
    Human KRT18-1585HFL Recombinant Full Length Human KRT18 Protein, N-His-tagged E.coli His
    Mouse KRT18-4914M Recombinant Mouse KRT18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse KRT18-4914M-B Recombinant Mouse KRT18 Protein Pre-coupled Magnetic Beads HEK293
    Mouse KRT18-1745M Recombinant Mouse Krt18 Protein, His-tagged E.coli His
    Mouse Krt18-5841M Recombinant Mouse Krt18 protein, His-tagged E.coli His
    Mouse KRT18-8821M Recombinant Mouse KRT18 Protein Mammalian Cell His
    Pig KRT18-5842P Recombinant Pig KRT18 protein, His & T7-tagged E.coli His/T7
    Rat KRT18-3315R Recombinant Rat KRT18 Protein Mammalian Cell His
    Rat KRT18-2971R-B Recombinant Rat KRT18 Protein Pre-coupled Magnetic Beads HEK293
    Rat Krt18-5843R Recombinant Rat Krt18 protein, His-tagged E.coli His
    Rat KRT18-2971R Recombinant Rat KRT18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Zebrafish KRT18-9605Z Recombinant Zebrafish KRT18 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    KRT18 involved in several pathways and played different roles in them. We selected most pathways KRT18 participated on our site, such as Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pathogenic Escherichia coli infectionTUBA8;TUBB2B;TUBB7P;RHOA;TUBA1A;TUBA4A;CTTN;TUBA3D;ROCK1

    KRT18 has several biochemical functions, for example, poly(A) RNA binding, protein binding, scaffold protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT18 itself. We selected most functions KRT18 had, and list some proteins which have the same functions with KRT18. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA bindingNOLC1;RAN;PSMC1;MYH9;GPATCH8;STXBP1;PRDX1;DDX18;DDX6
    protein bindingGPR19;SSB;MACROD1;VPS52;TIA1;MYO5B;RMI1;SPTAN1;INCENP
    scaffold protein bindingSCN5A;KRT8;CAV2;KRT5;GRID2;CASP8;DLG4;NLGN3;NCK2
    structural molecule activityCOPG;KRT27;PNN;TUBG2;CLDN7A;CLDN20;CLDN15;CLDN10;CLDNB

    KRT18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT18 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT18.

    KRT8; YWHAZ; DNAJB6; TRADD

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