Recombinant Full Length Human KRT18 Protein, N-His-tagged

• Cat.No.: KRT18-1585HFL
• Product Overview: Recombinant Full Length Human KRT18 Protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Description: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 47.9 kDa
• AA Sequence: A DNA sequence encoding human full-length KRT18.
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Pathogenic Escherichia coli infection

Gene Information

• Gene Name: KRT18 keratin 18 [ Homo sapiens (human) ]
• Official Symbol: KRT18
• Synonyms: K18; CK-18; CYK18
• Gene ID: 3875
• mRNA Refseq: NM_199187.2
• Protein Refseq: NP_954657.1
• MIM: 148070
• UniProt ID: P61769