Recombinant Human KRT18 protein, His-tagged

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Recombinant Human KRT18 protein, His-tagged

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Cat.No. : KRT18-12H
Product Overview : Recombinant Human KRT18, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
Description : KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass : 47.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : KRT18 keratin 18 [ Homo sapiens ]
Official Symbol : KRT18
Synonyms : KRT18; keratin 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; K18; CYK18;
Gene ID : 3875
mRNA Refseq : NM_000224
Protein Refseq : NP_000215
MIM : 148070
UniProt ID : P05783
Chromosome Location : 12q13
Pathway : Caspase cascade in apoptosis, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem;
Function : protein binding; structural molecule activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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