Recombinant Human KRT18 protein, His-tagged
Cat.No. : | KRT18-12H |
Product Overview : | Recombinant Human KRT18, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 47.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | KRT18 keratin 18 [ Homo sapiens ] |
Official Symbol : | KRT18 |
Synonyms : | KRT18; keratin 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; K18; CYK18; |
Gene ID : | 3875 |
mRNA Refseq : | NM_000224 |
Protein Refseq : | NP_000215 |
MIM : | 148070 |
UniProt ID : | P05783 |
Chromosome Location : | 12q13 |
Pathway : | Caspase cascade in apoptosis, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem; |
Function : | protein binding; structural molecule activity; |
Products Types
◆ Recombinant Protein | ||
KRT18-1075H | Recombinant Human KRT18 Protein, His-tagged | +Inquiry |
KRT18-1745M | Recombinant Mouse Krt18 Protein, His-tagged | +Inquiry |
KRT18-4867H | Recombinant Human KRT18 Protein, GST-tagged | +Inquiry |
KRT18-2971R | Recombinant Rat KRT18 Protein, His (Fc)-Avi-tagged | +Inquiry |
KRT18-174H | Recombinant Human KRT18 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
KRT18-173B | Native bovine KRT18 | +Inquiry |
◆ Lysates | ||
KRT18-4876HCL | Recombinant Human KRT18 293 Cell Lysate | +Inquiry |
KRT18-4877HCL | Recombinant Human KRT18 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionKRT18 protein may be associated with nail diseases, such as brittle nails, white spots, and longitudinal cracks. These diseases can affect the hardness and structure of the nails, causing them to appear brittle, deformed, and painful.
KRT18 protein is not directly related to hair color. Hair color is mainly determined by melanocytes, while the KRT18 protein is mainly involved in the process of keratinization.
Genetic testing can be done by analyzing DNA sequences to understand genetic variation in the KRT18 protein. These variants may affect the expression level and function of the KRT18 protein, thereby increasing the risk of certain diseases.
Lifestyle changes, such as eating a healthy diet, exercising moderately, and avoiding UV damage, can affect the function and expression levels of KRT18 protein. These alterations can promote the normal function of keratinocytes, which can help maintain healthy skin.
Prevention of KRT18 protein-related diseases is mainly through maintaining a healthy lifestyle, such as a balanced diet, moderate exercise, maintaining water intake, and avoiding UV damage. In addition, regular skin and oral exams can also help detect potential problems early.
In melanoma, the KRT18 protein may play a role in promoting tumor growth and metastasis. This may be related to the proliferation and migration of melanoma cells.
Customer Reviews (3)
Write a reviewThe sensitivity is very high, the experimental results are very good, and the unnecessary trouble is reduced.
No doping impurities, the experimental effect is very good, will be recommended to other laboratory students.
Easy to operate, cost-effective.
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