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LDH

Official Full Name

Tryptophan 2,3-dioxygenase
Overview

In enzymology, a tryptophan 2,3-dioxygenase (EC 1.13.11.11) is an enzyme that catalyzes the chemical reaction L-tryptophan + O2 = N-formyl-L-kynurenine Thus, the two substrates of this enzyme are L-tryptophan and O2, whereas its product is N-formyl-L-kynurenine. This enzyme participates in tryptophan metabolism.
Synonyms

TDO; TPH2; TRPO; Tryptophan 2,3-dioxygenase; Tryptophan Oxygenase; Tryptophan Pyrrolase; Tryptophanase;

Type

Native Proteins
Recombinant Proteins
Assay Kits
Others

Species

Bacillus cereus
Bacillus subtilis
Bovine
Chicken
Human
Lactobacillus casei
Pig
Plasmodium falciparum
Plasmodium knowlesi
Plasmodium malariae
Plasmodium ovale
Plasmodium vivax
Rabbit
Streptococcus pneumoniae

Source

Bovine Heart
Chicken Heart
E. coli or Yeast
E.coli
HEK293 cells
Human
Human Erythrocyte
Human Heart
Porcine Heart
Porcine Muscle
Rabbit Muscle

Tag

C
His
E. coli
N
Myc
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LDH-226H	Active Native Human Lactate Dehydrogenase Total	Human	Non		Inquiry
Human	LDH-17H	Active Native Human Lactate Dehydrogenase	Human Erythrocyte	Non		Inquiry
Human	LDH-227H	Active Native Human Lactate Dehydrogenase Total	Human Erythrocyte	Non		Inquiry
Human	LDH-15H	Native Human Lactate Dehydrogenase	Human Heart	Non		Inquiry
Human	LDH-228H	Native Human Lactate Dehydrogenase Total	Human Heart	Non		Inquiry
Rabbit	LDH-217R	Active Native Rabbit Lactate Dehydrogenase	Rabbit Muscle	Non		Inquiry
Bacillus cereus	ldh-1631B	Recombinant Bacillus cereus ldh Protein (Full Length), His tagged	E.coli	His	Full Length	Inquiry
Bacillus cereus	ldh-1632B	Recombinant Bacillus cereus ldh Protein (Thr2-Arg366), His tagged	E.coli	His	Thr2-Arg366	Inquiry
Bacillus subtilis	LDH-0507B	Recombinant Bacillus subtilis LDH protein, His-tagged	E. coli or Yeast	His		Inquiry
Bovine	LDH-121B	Active Native Bovine Lactate Dehydrogenase	Bovine Heart	Non		Inquiry
Lactobacillus casei	ldh-632L	Recombinant Lactobacillus casei ldh protein, His-tagged	E.coli	C-His	2-326aa	Inquiry
Plasmodium falciparum	LDH-66P	Recombinant Pf LDH Protein	E.coli			Inquiry
Plasmodium knowlesi	LDH-69P	Recombinant Pk LDH Protein	E.coli			Inquiry
Plasmodium malariae	LDH-70P	Recombinant Pm LDH Protein	E.coli			Inquiry
Plasmodium ovale	LDH-71P	Recombinant Po LDH Protein	E.coli			Inquiry
Plasmodium vivax	LDH-0124P	Recombinant Plasmodium vivax LDH antigen	HEK293 cells			Inquiry
Plasmodium vivax	LDH-72P	Recombinant Pv LDH Protein	E.coli			Inquiry
Streptococcus pneumoniae	ldh-7548S	Recombinant Streptococcus pneumoniae (strain P1031) ldh protein(1-328aa), His&Myc-tagged	E.coli	N-His&C-Myc	1-328aa	Inquiry
Pig	LDH-215S	Active Native Porcine Lactate Dehydrogenase	Porcine Heart	Non		Inquiry
Pig	LDH-216S	Active Native Porcine Lactate Dehydrogenase	Porcine Muscle	Non		Inquiry
Chicken	LDH-35C	Active Native Chicken Lactate dehydrogenase	Chicken Heart	Non		Inquiry
	Kit-0510	Lactate Dehydrogenase B (LDHB) Activity Assay Kit		Non		Inquiry
	Kit-2194	LDH-Cytotoxicity Fluorometric Assay Kit		Non		Inquiry
	PLA-537	Recombinant Plasmodium Falciparum LDH Protein		E. coli		Inquiry
	Kit-0509	Lactate Dehydrogenase Assay Kit		Non		Inquiry
	Kit-2087	L-Lactate Dehydrogenase Assay Kit		Non		Inquiry
	Kit-1072	LDH-Cytotoxicity Colorimetric Assay Kit II		Non		Inquiry
	PLA-539	Recombinant Plasmodium Vivax LDH Protein		E. coli		Inquiry
	Kit-2088	D-Lactate Dehydrogenase Assay Kit		Non		Inquiry
	Kit-2257	Lactate Dehydrogenase Activity Assay Kit		Non		Inquiry
	Kit-0511	LDH-Cytotoxicity Assay Kit		Non		Inquiry
	Kit-2203	Lactate Dehydrogenase Activity Colorimetric Assay Kit (384-well)		Non		Inquiry

Other Resource

LDH involved in several pathways and played different roles in them. We selected most pathways LDH participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LDH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

LDH has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LDH itself. We selected most functions LDH had, and list some proteins which have the same functions with LDH. You can find most of the proteins on our site.

Function	Related Protein

LDH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDH here. Most of them are supplied by our site. Hope this information will be useful for your research of LDH.

Research Area

Lahiani, A; Zahavi, E; et al. Human PLacental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1853:422-430(2015).

Yang, QS; Guo, SF; et al. Advanced glycation end products-induced chondrocyte apoptosis through mitochondrial dysfunction in cultured rabbit chondrocyte. FUNDAMENTAL & CLINICAL PHARMACOLOGY 29:54-61(2015).