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Official Full Name melanoma antigen family A, 6
Background This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
Synonyms MAGEA6; melanoma antigen family A, 6; MAGE6; melanoma-associated antigen 6; cancer/testis antigen family 1; member 6; CT1.6; MAGE 6 antigen; melanoma antigen family A 6; melanoma associated antigen 6; Cancer/testis antigen 1.6; MAGA6_HUMAN; MAGE 3b; MAGE-6 antigen; MAGE3B; MAGE3B antigen; OTTHUMP00000024223; OTTHUMP00000024224; OTTHUMP00000205538; cancer/testis antigen family 1, member 6; MAGE-3b
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAGEA6-232H Recombinant Human MAGEA6 protein, T7/His-tagged E.coli T7/His
    Human MAGEA6-30166TH Recombinant Human MAGEA6 Wheat Germ N/A
    Human MAGEA6-403H Recombinant Human MAGEA6 Mammalian Cell His
    Human MAGEA6-4551HCL Recombinant Human MAGEA6 293 Cell Lysate HEK293 N/A
    Human MAGEA6-6788H Recombinant Human Melanoma Antigen Family A, 6, His-tagged E.coli His

    magea6 involved in several pathways and played different roles in them. We selected most pathways magea6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with magea6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    magea6 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by magea6 itself. We selected most functions magea6 had, and list some proteins which have the same functions with magea6. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function GM106; TMEM188; TTLL9; ZFAND5; MCART1; NES; FAM105A; TP53I11B; HERPUD1; KHDC1C
    protein binding CLOCK; HOXB9; CD22; SSR1; TALDO1; MAP6; TSNAX; MRPS16; MRPL10; MAGEE1

    magea6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with magea6 here. Most of them are supplied by our site. Hope this information will be useful for your research of magea6.


    Lee, OJ; Son, SM; et al. CEACAM6 as detected by the AP11 antibody is a marker notable for mucin-producing adenocarcinomas. VIRCHOWS ARCHIV 466:151-159(2015).
    Zhang, QM; He, SJ; et al. Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3918-3927(2014).

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