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MED11

  • Official Full Name

    mediator complex subunit 11

  • Overview

    MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
  • Synonyms

    MED11; mediator complex subunit 11; HSPC296; mediator of RNA polymerase II transcription subunit 11; mediator of RNA polymerase II transcription, subunit 11 homolog;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MED11-874H Recombinant Human MED11 Protein, His-tagged E.coli His
Human MED11-4480H Recombinant Human MED11 Protein, GST-tagged Wheat Germ GST
Human MED11-6130HF Recombinant Full Length Human MED11 Protein, GST-tagged In Vitro Cell Free System GST 117 amino acids
Mouse MED11-9681M Recombinant Mouse MED11 Protein Mammalian Cell His
Mouse MED11-5442M-B Recombinant Mouse MED11 Protein Pre-coupled Magnetic Beads HEK293
Mouse MED11-5442M Recombinant Mouse MED11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MED11-2717R Recombinant Rhesus monkey MED11 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MED11-2537R Recombinant Rhesus Macaque MED11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MED11-2537R-B Recombinant Rhesus Macaque MED11 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MED11-7468Z Recombinant Zebrafish MED11 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MED11 involved in several pathways and played different roles in them. We selected most pathways MED11 participated on our site, such as Mus musculus biological processes, Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mus musculus biological processesSYNE2;KLF5;SYCE2;POT1A;MED11;SYCP1;SUN2
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytesMED11;KLF5

MED11 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, protein binding, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED11 itself. We selected most functions MED11 had, and list some proteins which have the same functions with MED11. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription cofactor activityPPARGC1A;MED4;MED30;MED17;MED19;MED31;MED10;FOXH1;MED20
protein bindingMGAT5B;NUTF2;MTA2;AP2B1;COPS4;MAPK8;ARL6IP1;SMAD5;ZFP36L1
contributes_to ubiquitin protein ligase activityFBXL7;CUL4A;KDM2BA;FBXL15;CUL5;FBXL5;CUL1A;FBXL6;CUL2

MED11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED11.

MED6; MED22; MED27; MED18; Med30; Med8; MED28; MED17; MED29; Ywhae; Cdk9

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