MGAT5

  • Official Full Name

    mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

  • Synonyms

    MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT V; glcNAc-T V; N-acetylglucosaminyl-transferase V; mannoside acetylglucosaminyltransferase 5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
  • N
  • 6×His, GFP
  • Tag
  • Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MGAT5-1120H Active Recombinant Human MGAT5 protein, His-tagged HEK293 His Leu189-Leu741
Human MGAT5-2067HCL Recombinant Human MGAT5 cell lysate Human Cell N/A
Human MGAT5-4363H Recombinant Human MGAT5 Protein, GST-tagged Wheat Germ GST
Human MGAT5-04H Recombinant Human MGAT5 Protein (AA 31-741), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 31-741
Rattus norvegicus (Rat) RFL25525RF Recombinant Full Length Rat Alpha-1,6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase A(Mgat5) Protein, Tag-Free E.coli expression system Tag-Free Full Length (1-740)
Zebrafish MGAT5-4300Z Recombinant Zebrafish MGAT5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

MGAT5 involved in several pathways and played different roles in them. We selected most pathways MGAT5 participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGAT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
N-Glycan biosynthesisALG13;MGAT3;MAN1A;ALG2;ALG3;ALG6;FUT8A;MGAT1;MAN1A2
Metabolic pathwaysCMBL;ACSS1;CMASA;POLD4;GUK1;UPP2;CYP3A5;PCYT1BB;PRPS1B

MGAT5 has several biochemical functions, for example, alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MGAT5 itself. We selected most functions MGAT5 had, and list some proteins which have the same functions with MGAT5. You can find most of the proteins on our site.

Function Related Protein
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activityMGAT5B;MGAT5;CCDC126

MGAT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGAT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MGAT5.

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Research Area

Related articles

Dos-Santos, PB; Zanetti, JS; et al. Lectin histochemistry reveals SNA as a prognostic carbohydrate-dependent probe for invasive ductal carcinoma of the breast: a clinicopathological and immunohistochemical auxiliary tool. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:2337-2349(2014).
Blomme, B; Heindryckx, F; et al. Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor. MOLECULAR AND CELLULAR BIOCHEMISTRY 372:199-210(2013).
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  • Q&As

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        Q&As (7)

        Ask a question
        What role does MGAT5 play in immune responses? 07/24/2022

        MGAT5 modulates immune responses.

        What is the primary role of MGAT5 in glycoprotein synthesis? 12/24/2021

        MGAT5 is key for glycoprotein glycosylation.

        How does MGAT5 contribute to cell signaling and communication? 09/09/2021

        It affects cell signaling by altering glycosylation patterns.

        What is the impact of altered MGAT5 activity on cancer progression? 09/06/2021

        Altered MGAT5 activity is linked to cancer progression.

        How do genetic variations in MGAT5 affect cellular functions? 03/22/2020

        Genetic changes in MGAT5 impact glycosylation and cell processes.

        What potential therapeutic applications arise from targeting MGAT5 in diseases? 01/29/2020

        Targeting MGAT5 could treat diseases involving abnormal glycosylation.

        How does MGAT5 interact with other enzymes in glycosylation pathways? 06/08/2019

        MGAT5 collaborates with other enzymes in glycosylation.

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