Recombinant Human MGAT5 Protein, GST-tagged

• Cat.No.: MGAT5-4363H
• Product Overview: Human MGAT5 partial ORF ( NP_002401, 642 a.a. - 739 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded proteins activity may correlate with the progression of invasive malignancies. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.52 kDa
• AA Sequence: LAEPGQSCKQVCQESQLICEPSFFQ HLNKDKDMLKYKVTCQSSELAKDIL VPSFDPKNKHCVFQGDLLLFSCAGA HPRHQRVCPCRDFIKGQVALCKD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [ Homo sapiens ]
• Official Symbol: MGAT5
• Synonyms: MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT V; glcNAc-T V; N-acetylglucosaminyl-transferase V; mannoside acetylglucosaminyltransferase 5; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GNT-V; GNT-VA; FLJ31899; FLJ43217; DKFZp686B24166
• Gene ID: 4249
• mRNA Refseq: NM_002410
• Protein Refseq: NP_002401
• MIM: 601774
• UniProt ID: Q09328

Reviews

02/19/2023

Trusted for research integrity, a dependable research collaborator.

10/07/2020

Efficient service, accelerates research progress.

11/24/2018

Outstanding accuracy, an essential part of our research.

Q&As

What role does MGAT5 play in immune responses?

MGAT5 modulates immune responses.

What is the primary role of MGAT5 in glycoprotein synthesis?

MGAT5 is key for glycoprotein glycosylation.

How does MGAT5 contribute to cell signaling and communication?

It affects cell signaling by altering glycosylation patterns.

What is the impact of altered MGAT5 activity on cancer progression?

Altered MGAT5 activity is linked to cancer progression.

How do genetic variations in MGAT5 affect cellular functions?

Genetic changes in MGAT5 impact glycosylation and cell processes.

What potential therapeutic applications arise from targeting MGAT5 in diseases?

Targeting MGAT5 could treat diseases involving abnormal glycosylation.

How does MGAT5 interact with other enzymes in glycosylation pathways?

MGAT5 collaborates with other enzymes in glycosylation.