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MRPL42

Official Full Name

mitochondrial ribosomal protein L42
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
Synonyms

MRPL42; mitochondrial ribosomal protein L42; 39S ribosomal protein L42, mitochondrial; HSPC204; MRP L31; MRPL31; MRPS32; PTD007; RPML31; mitochondrial; 28S ribosomal protein S32; 39S ribosomal protein L31; 39S ribosomal protein L42; L31mt; L42mt; Mitochondrial ribosomal protein S32; MRP L42; MRP S32; MRP-L31; MRP-L42; MRP-S32; RM42_HUMAN; S32mt; 28S ribosomal protein S32, mitochondrial; 39S ribosomal protein L31, mitochondrial;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL42-4167HCL	Recombinant Human MRPL42 293 Cell Lysate	HEK293	Non		Inquiry
Human	MRPL42-3243H	Recombinant Human MRPL42 protein, GST-tagged	E.coli	GST	33-142aa	Inquiry
Human	MRPL42-3365H	Recombinant Human MRPL42 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	MRPL42-10069M	Recombinant Mouse MRPL42 Protein	Mammalian Cell	His		Inquiry
Mouse	MRPL42-5703M	Recombinant Mouse MRPL42 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	Mrpl42-4157M	Recombinant Mouse Mrpl42 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	MRPL42-5703M-B	Recombinant Mouse MRPL42 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPL42 involved in several pathways and played different roles in them. We selected most pathways MRPL42 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL55;MRPS25;MRPL49;MRRF;CHCHD1;MRPL40;MRPL50;GFM2;MRPS30
Mitochondrial translation elongation	MRPS25;MRPS31;MRPL49;MRPL53;MRPS23;MRPS26;MRPS24;MRPL47;MRPS30
Mitochondrial translation initiation	MRPS35;PTCD3;MRPS30;MRPL53;MRPL52;MRPS28;MRPS34;MRPL41;MRPL10
Mitochondrial translation termination	MRPS30;MRPS28;MRPS35;MRPL47;MRPL45;MRPL49;MRPS33;MRPS22;MRPL50
Organelle biogenesis and maintenance	CLUAP1;MRPL54;MRPL38;MRPS22;TTC30A2;UNC119B;GADD45GIP1;EXOC8;MRPL37

MRPL42 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL42 itself. We selected most functions MRPL42 had, and list some proteins which have the same functions with MRPL42. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	NXF2;NOP2;NUPL2;ANXA7;RPUSD3;RPP30;HLA-A;PTRF;AATF
structural constituent of ribosome	RPS9;MRPL1;RPS26L;RPL27A;MRPS21;RPS12;RPL10L;FAUB;RPL13

MRPL42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL42 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL42.

rev; IKBKAP; EEF1A1