• Official Full Name

    mitochondrial ribosomal protein L42

  • Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
  • Synonyms

    MRPL42; mitochondrial ribosomal protein L42; 39S ribosomal protein L42, mitochondrial; HSPC204; MRP L31; MRPL31; MRPS32; PTD007; RPML31; mitochondrial; 28S ribosomal protein S32; 39S ribosomal protein L31; 39S ribosomal protein L42; L31mt; L42mt; Mitochondrial ribosomal protein S32; MRP L42; MRP S32; MRP-L31; MRP-L42; MRP-S32; RM42_HUMAN; S32mt; 28S ribosomal protein S32, mitochondrial; 39S ribosomal protein L31, mitochondrial;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MRPL42-3243H Recombinant Human MRPL42 protein, GST-tagged E.coli GST
    Human MRPL42-4167HCL Recombinant Human MRPL42 293 Cell Lysate HEK293 N/A
    Human MRPL42-3365H Recombinant Human MRPL42 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse MRPL42-5703M Recombinant Mouse MRPL42 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Mrpl42-4157M Recombinant Mouse Mrpl42 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse MRPL42-5703M-B Recombinant Mouse MRPL42 Protein Pre-coupled Magnetic Beads HEK293
    Mouse MRPL42-10069M Recombinant Mouse MRPL42 Protein Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    MRPL42 involved in several pathways and played different roles in them. We selected most pathways MRPL42 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial translationDAP3;MRPL49;MRPL40;MRPS33;MRPL52;GFM2;AURKAIP1;MRPL51;MRPS25
    Mitochondrial translation elongationMRPL47;MRPL3;MRPL42;MRPL49;MRPL53;MRPL41;MRPL52;MRPS27;MRPS30
    Mitochondrial translation initiationMRPL54;MRPS36;MTFMT;MRPS27;MTIF3;MRPS22;MRPL50;MRPS26;MRPL46
    Mitochondrial translation terminationMRPL28;CHCHD1;DAP3;PTCD3;MRPS34;MRPL48;MRPS22;MRPL53;MRPS26
    Organelle biogenesis and maintenanceMRPS22;TRIP11;PKD1;IFT80;KIF3CB;TUFM;TTC8;MRPL45;IFT122

    MRPL42 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL42 itself. We selected most functions MRPL42 had, and list some proteins which have the same functions with MRPL42. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA bindingAKAP8;ALKBH5;MOV10;RG9MTD1;PTBP2;MRPS21;C14orf93;NCBP2;DIMT1
    structural constituent of ribosomeMRPL52;MRPL51;RPS19;RPL7;FAUA;MRPL3;RPS4X;MRPS2;MRPS6

    MRPL42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL42 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL42.

    rev; IKBKAP; EEF1A1

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