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Official Full Name non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
Background Nucleoside diphosphate (NDP) kinases (EC, such as NME6, are ubiquitous enzymes that catalyze transfer of;gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates;(Mehus et al., 1999 (PubMed 10453732)).
Synonyms NME6; non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase); nucleoside diphosphate kinase 6; IPIA ALPHA; NM23 H6; NDP kinase 6; inhibitor of p53-induced apoptosis-alpha; NDK 6; NM23-H6; IPIA-ALPHA
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NME6-1315H Recombinant Human NME6, GST-tagged E.coli GST
    Human NME6-1456H Recombinant Human NME6 protein, His & T7-tagged E.coli His/T7
    Human NME6-207H Recombinant Human NME6 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human NME6-3787HCL Recombinant Human NME6 293 Cell Lysate HEK293 N/A
    Human NME6-5934H Recombinant Human NME6 Protein, GST-tagged Wheat Germ GST
    Mouse NME6-10743M Recombinant Mouse NME6 Protein Mammalian Cell His
    Mouse Nme6-1457M Recombinant Mouse Nme6 protein, His-tagged E.coli His
    Mouse Nme6-4439M Recombinant Mouse Nme6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat Nme6-1458R Recombinant Rat Nme6 protein, His & T7-tagged E.coli His/T7
    Cynomolgus Monkey NME6-749C Recombinant Cynomolgus NME6 Protein, His-tagged Mammalian Cell His
    Zebrafish NME6-9138Z Recombinant Zebrafish NME6 Mammalian Cell His

    nme6 involved in several pathways and played different roles in them. We selected most pathways nme6 participated on our site, such as Biosynthesis of antibiotics, CMP phosphorylation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with nme6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biosynthesis of antibiotics DLAT; ECHS1; AKR1A1; ADH5; LDHAL6A; LDHAL6B; EHHADH; AGXT; PAICS; CTH
    CMP phosphorylation CMPK2; NME6
    Metabolic pathways CTPS1A; MTMR3; CBR1; CYP3A65; B4GALT4; LPIN3; COX7B2; ACLY; CERS2; NDUFS5
    Purine metabolism GUK1; AK4; POLD2; AK3; RRM1; ADCY1A; PAICS; POLR3GLB; ENPP4; NUDT9
    Pyrimidine metabolism POLR2L; TXNRD3; NT5C1A; POLR2GL; NT5C3B; POLE2; POLD1; POLR2E; TK1; NME6
    UTP and CTP de novo biosynthesis NME6; CMPK2
    adenosine deoxyribonucleotides de novo biosynthesis NME6
    guanosine deoxyribonucleotides de novo biosynthesis NME6

    nme6 has several biochemical functions, for example, ATP binding, metal ion binding, nucleoside diphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by nme6 itself. We selected most functions nme6 had, and list some proteins which have the same functions with nme6. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding SRPK2; STK26; CDK11A; DMC1; SPO11; PAK3; PMVK; ABL2; ENTPD3; INSRA
    metal ion binding AMPD3; TRAFD1; ATP13A1; ZBTB11; TRIM35-20; ZNF200; KARS; ALPL; ZC4H2; SDF4
    nucleoside diphosphate kinase activity AK7; AK5; NME2A; NME3; NME1; AK9; NME2B.2; NME4; NME7; CMPK1

    nme6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with nme6 here. Most of them are supplied by our site. Hope this information will be useful for your research of nme6.


    Haglund, S; Almer, S; et al. Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease - Novel Clues to Drug Targets and Disease Mechanisms?. PLOS ONE 8:-(2013).
    Wang, CH; Ma, NH; et al. A shRNA Functional Screen Reveals Nme6 and Nme7 Are Crucial for Embryonic Stem Cell Renewal. STEM CELLS 30:2199-2211(2012).

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