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NME6

  • Official Full Name

    non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)

  • Overview

    Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of;gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates;(Mehus et al., 1999 (PubMed 10453732)).
  • Synonyms

    NME6; non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase); nucleoside diphosphate kinase 6; IPIA ALPHA; NM23 H6; NDP kinase 6; inhibitor of p53-induced apoptosis-alpha; NDK 6; NM23-H6; IPIA-ALPHA;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NME6-1315H Recombinant Human NME6, GST-tagged E.coli GST 1-194aa
Human NME6-3787HCL Recombinant Human NME6 293 Cell Lysate HEK293 N/A
Human NME6-3314H Recombinant Human NME6 protein, His-tagged E.coli His 1-194 aa
Human NME6-5934H Recombinant Human NME6 Protein, GST-tagged Wheat Germ GST
Human NME6-6587HF Recombinant Full Length Human NME6 Protein, GST-tagged In Vitro Cell Free System GST 194 amino acids
Human NME6-1456H Recombinant Human NME6 protein, His & T7-tagged E.coli His/T7 Ser3~Gly182 (Accession # O75414)
Human NME6-207H Recombinant Human NME6 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NME6-3870H Recombinant Human NME6 Protein (Leu11-Ala190), His tagged E.coli His Leu11-Ala190
Human NME6-3871H Recombinant Human NME6 Protein (Leu11-Ala186), N-His tagged E.coli N-His Leu11-Ala186
Mouse NME6-10743M Recombinant Mouse NME6 Protein Mammalian Cell His
Mouse Nme6-4439M Recombinant Mouse Nme6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Nme6-1457M Recombinant Mouse Nme6 protein, His-tagged E.coli His Met1~Lys184 (Accession # O88425)
Mouse NME6-6112M-B Recombinant Mouse NME6 Protein Pre-coupled Magnetic Beads HEK293
Mouse NME6-6112M Recombinant Mouse NME6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Nme6-1458R Recombinant Rat Nme6 protein, His & T7-tagged E.coli His/T7 Cys13~Ala241 (Accession # O88426)
Cynomolgus Monkey NME6-749C Recombinant Cynomolgus NME6 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey NME6-493C Recombinant Cynomolgus Monkey NME6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey NME6-493C-B Recombinant Cynomolgus Monkey NME6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NME6-9138Z Recombinant Zebrafish NME6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NME6 Related Articles

NME6 involved in several pathways and played different roles in them. We selected most pathways NME6 participated on our site, such as Biosynthesis of antibiotics, CMP phosphorylation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NME6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biosynthesis of antibioticsCS;ECHS1;ADSL;DLST;SDSL;pykF;AKR1A1;BPNT1;CYP51A1
CMP phosphorylationCMPK2;NME6
Metabolic pathwaysUQCRC1;CKM;GRHPRA;DPYD;PTGDSB;MAN2A1;GALNT6;ATP6V1C2;PON3
Purine metabolismGUCY2E;PNP;POLR3GLB;NME2;PFAS;ADSS;NT5C2A;GMPR2;POLR2EB
Pyrimidine metabolismTYMS;DPYDB;POLE2;NME2B.1;POLR1E;POLR2K;TYMP;POLR2A;NME2A
UTP and CTP de novo biosynthesisCMPK2;NME6
adenosine deoxyribonucleotides de novo biosynthesis
guanosine deoxyribonucleotides de novo biosynthesis

NME6 has several biochemical functions, for example, ATP binding, metal ion binding, nucleoside diphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NME6 itself. We selected most functions NME6 had, and list some proteins which have the same functions with NME6. You can find most of the proteins on our site.

Function Related Protein
ATP bindingACVRL1;TTLL3;NLRC3;OASL2;ACSM3;SYN2;MYH1E;SKIV2L2;DCLK1A
metal ion bindingTSHZ3;ZFP512;PTGS2;NAIP1;TRIM35-27;ZSCAN4C;ZBTB8A;BTR06;FGD
nucleoside diphosphate kinase activityAK7;NME4;CMPK;NME2B.1;CMPK1;NME9;AK9;NME6;NME8

NME6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NME6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NME6.

SSSCA1; WBSCR16

Haglund, S; Almer, S; et al. Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease - Novel Clues to Drug Targets and Disease Mechanisms?. PLOS ONE 8:-(2013).
Wang, CH; Ma, NH; et al. A shRNA Functional Screen Reveals Nme6 and Nme7 Are Crucial for Embryonic Stem Cell Renewal. STEM CELLS 30:2199-2211(2012).
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