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NR2C2

  • Official Full Name

    NR2C2 nuclear receptor subfamily 2, group C, member 2

  • Overview

    Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The;proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a;ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it;binds to hormone response elements of target genes (Yoshikawa et al., 1996 (PubMed 8661150)).
  • Synonyms

    NR2C2; nuclear receptor subfamily 2, group C, member 2; TR4; nuclear receptor subfamily 2 group C member 2; hTAK1; TAK1; TR2R1; testicular receptor 4; orphan nuclear receptor TR4; Nuclear hormone receptor TR4; TR4 nuclear hormone receptor; orphan nuclear receptor TAK1; testicular nuclear receptor 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR2C2-1089H Recombinant Human NR2C2 protein, His & T7-tagged E.coli His/T7 Leu371~Leu596 (Accession # P49116)
Human NR2C2-3713HCL Recombinant Human NR2C2 293 Cell Lysate HEK293 N/A
Human NR2C2-6079H Recombinant Human NR2C2 Protein, GST-tagged Wheat Germ GST
Human NR2C2-1538H Recombinant Human NR2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NR2C2-1900HFL Recombinant Full Length Human NR2C2 Protein, C-Flag-tagged Mammalian cells Flag
Human NR2C2-6737HF Recombinant Full Length Human NR2C2 Protein, GST-tagged In Vitro Cell Free System GST 530 amino acids
Human NR2C2-1538H-B Recombinant Human NR2C2 Protein Pre-coupled Magnetic Beads HEK293
Human NR2C2-5145H Recombinant Human NR2C2 Protein (Ile25-Pro579), His tagged E.coli His Ile25-Pro579
Human NR2C2-5146H Recombinant Human NR2C2 Protein (Arg191-Pro503), N-His tagged E.coli N-His Arg191-Pro503
Mouse NR2C2-10862M Recombinant Mouse NR2C2 Protein Mammalian Cell His
Mouse NR2C2-6184M Recombinant Mouse NR2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nr2c2-4488M Recombinant Mouse Nr2c2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NR2C2-6184M-B Recombinant Mouse NR2C2 Protein Pre-coupled Magnetic Beads HEK293
Rat NR2C2-4066R Recombinant Rat NR2C2 Protein Mammalian Cell His
Rat NR2C2-3725R Recombinant Rat NR2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NR2C2-3725R-B Recombinant Rat NR2C2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NR2C2-6678Z Recombinant Zebrafish NR2C2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NR2C2 Related Signal Pathway

NR2C2 involved in several pathways and played different roles in them. We selected most pathways NR2C2 participated on our site, such as Androgen receptor signaling pathway, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR2C2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Androgen receptor signaling pathwayCTNNB1;AES;PNRC1;KAT7;DSTN;SMARCE1;DAXX;RNF6;RHOB
Gene ExpressionSNAPC1;HNRNPA0;TNPO1;TET2;RXRBB;ZNF483;ZNF468;ZNF583;RARAA
Generic Transcription PathwayNR6A1A;COX6A1;ZFP37;MED15;SKIA;ZNF691;ZNF606;ZNF701;ZFP30
Nuclear Receptor transcription pathwayNR2F1;NR2C2;NR5A1B;NR1H3;RORAA;ESRRGA;NR0B2A;NR2F1B;RARAB
Nuclear ReceptorsRARGB;NR1D2B;NR1I3;NR2F1A;NR4A2A;RARG;RORAA;NR2F1;NR2F6
Regulation of Androgen receptor activityKAT7;SENP1;TRIM24;SMARCE1;NR2C2;NR0B1;SRY;SMARCA2;HOXB13
TNF-alpha/NF-kB Signaling PathwayDDX3X;DPF2;KPNA6;DAP;UNC5CL;LRPPRC;MARK2;COPS3;TIFA

NR2C2 has several biochemical functions, for example, protein binding, protein heterodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NR2C2 itself. We selected most functions NR2C2 had, and list some proteins which have the same functions with NR2C2. You can find most of the proteins on our site.

Function Related Protein
protein bindingTNKS2;ERBB4;FAM109A;PYGO2;CD9;TCP1;MYL12A;SP100;TBCA
protein heterodimerization activityBOK;NEUROD2;KCNH1;KHDRBS2;VEGFA;P2RY1;RRAGC;PVRL1;CENPW
receptor activityHTR3A;NLGN4X;GFRA4A;TRAM1;ANTXRL;NLGN1;ANTXR2B;NOTCH1;SLC20A1
sequence-specific DNA bindingDBX1A;FOXJ3;E2F5;ESRRA;NCOR1;VSX2;EOMES;ZFP13;POU2F3
steroid hormone receptor activityNR2E1;THRAA;ESR2B;PAQR7B;NR2F1;NR0B2;NR4A3;PGRMC2;PGR
transcription coactivator activityTRIM32;RB1;JUPA;ASXL1;NR5A1;KAT2B;MMS19;CDK7;CALCOCO1
transcription factor activity, sequence-specific DNA bindingE2F3;PGBD1;ESRRGB;IRF6;ZFP821;HOXB7A;CREB5;SIX4;ZNF354A
zinc ion bindingADAM21;PGLYRP5;RYBPB;BRD1B;DPEP1;MIB2;MMP24;FTR54;MANEA

NR2C2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR2C2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR2C2.

HSP90AB1; KDM1A; CD2AP; AIM2; PRPF40A; EED; S100A4; RPP38; SNW1; PYHIN1; Tab1; KLHL7; SMARCC1; PATZ1; TANC2; RBMX2

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