Recombinant Human NR2C2 Protein, GST-tagged

• Cat.No.: NR2C2-6079H
• Product Overview: Human NR2C2 full-length ORF ( AAH51670.1, 1 a.a. - 530 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.9 kDa
• AA Sequence: MTSPSPRIQIISTDSAVASPQRIQG SEPASGPLSVFTSLNKEKIVTDQQT GQKIQIVTAVDASGSPKQQFTLTSP DGAGTGKVILASPETSSAKQLIFTT SDNLVPGRIQIVTDSASVERLLGKT DVQRPQVVEYCVVCGDKASGRHYGA VSCEGCKGFFKRSVRKNLTYSCRSN QDCIINKHHRNRCQFCRLKKCLEMG MKMESVQSKRKPFDVQREKPSNCAA STEKIYIRKDLRSPLIATPTFVADK DGARQTGLLDPGMLVNIQQPLIRED GTVLLATDSKAETSQGALGTLANVV TSLANLSESLNNGDTSEIQPEDQSA SEITRAFDTLAKALNTTDSSSSPSL ADGIDTSGGGSIHVISRDQSTPIIE VEGPLLSDTHVTFKLTMPSPMPEYL NVHYICESASRLLFLSMHWARSIPA FQALGQDCNTSLVRACWNELFTLGL AQCAQVMSLSTILAAIVNHLQNSIQ EDKLSGDRIKQVMEHIWKLQEFCNS MAKLDIDGYEYAYLKAIVLFSPGKI CGGDA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NR2C2 nuclear receptor subfamily 2, group C, member 2 [ Homo sapiens ]
• Official Symbol: NR2C2
• Synonyms: NR2C2; nuclear receptor subfamily 2, group C, member 2; TR4; nuclear receptor subfamily 2 group C member 2; hTAK1; TAK1; TR2R1; testicular receptor 4; orphan nuclear receptor TR4; Nuclear hormone receptor TR4; TR4 nuclear hormone receptor; orphan nuclear receptor TAK1; testicular nuclear receptor 4
• Gene ID: 7182
• mRNA Refseq: NM_003298
• Protein Refseq: NP_003289
• MIM: 601426
• UniProt ID: P49116