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Official Full Name ornithine carbamoyltransferase
Background This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Synonyms OTC; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; OTCase; ornithine transcarbamylase; OCTD; MGC129967; MGC129968; MGC138856
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • DDK
    • His
    • SUMO
    • T7
    • Myc/DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human OTC-1475H Recombinant Human OTC protein, His-tagged E.coli His
    Human OTC-325H Recombinant Human OTC Protein, His-tagged E.coli His
    Human OTC-452H Recombinant Human OTC Protein, DDK-tagged Insect Cell DDK
    Human OTC-6720H Recombinant Human OTC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse OTC-12224M Recombinant Mouse OTC Protein Mammalian Cell His
    Mouse Otc-7040M Recombinant Mouse Otc protein, His & T7-tagged E.coli His/T7
    Mouse OTC-705M Recombinant Mouse OTC Protein (33-354 aa), His-SUMO-tagged E.coli His/SUMO
    Rat OTC-4215R Recombinant Rat OTC Protein Mammalian Cell His
    Chicken OTC-6472C Recombinant Chicken OTC Mammalian Cell His

    otc involved in several pathways and played different roles in them. We selected most pathways otc participated on our site, such as Arginine biosynthesis, Metabolic pathways, Biosynthesis of amino acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with otc were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arginine biosynthesis GOT2; GLUD1A; NOS3; GPT; NOS2; GOT2B; GLSA; GLULA; GLULB; CPS1
    Metabolic pathways HDC; PKMB; NFS1; ST8SIA5; ACOX2; ARG2; CCBL1; PCYT2; IMPDH1A; DLDH
    Biosynthesis of amino acids MAT2AL; PRPS1; TKTL2; GOT2B; PFKMB; PKLR; PRPS1B; GOT2; GLUL; CTH

    otc has several biochemical functions, for example, amino acid binding, ornithine carbamoyltransferase activity, phosphate ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by otc itself. We selected most functions otc had, and list some proteins which have the same functions with otc. You can find most of the proteins on our site.

    Function Related Protein
    amino acid binding TH; DDC; TPH1B; DDAH1; DPYS; PAH; TPH1A; AARS; OTC; SHMT2
    ornithine carbamoyltransferase activity OTC
    phosphate ion binding ADSSL1; SH2B3; MTHFD2; SLC34A2; G6PC; RELA; ADSS; RPH3A; GNG12; PNP
    phospholipid binding APOEB; PLEKHA3; ABCG1; SYTL4; NBEA; MYOF; SGIP1; PACSIN1; SEC14L2; BAD

    otc has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with otc here. Most of them are supplied by our site. Hope this information will be useful for your research of otc.

    Mendling, W; et al. Guideline: Vulvovaginal Candidosis (AWMF 015/072), S2k (excluding chronic mucocutaneous candidosis). MYCOSES 58:1-15(2015).
    Wongtangprasert, T; Natakuathung, W; et al. Production of a monoclonal antibody against oxytetracycline and its application for oxytetracycline residue detection in shrimp. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B 15:165-172(2014).

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