P2RX7

  • Official Full Name

    P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7

  • Synonyms

    P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 purinoceptor; purinergic receptor P2X7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human P2RX7-1219H Active Recombinant Human P2RX7 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human P2RX7-1494H Recombinant Human P2RX7, GST-tagged E.coli GST C-term-350aa
Human P2RX7-3495HCL Recombinant Human P2RX7 293 Cell Lysate HEK293 N/A
Human P2RX7-6868HF Recombinant Full Length Human P2RX7 Protein, GST-tagged In Vitro Cell Free System GST 595 amino acids
Human P2RX7-391H Recombinant Human P2RX7 Protein, His-tagged E.coli His Ser47~Val334
Human P2RX7-4779H Recombinant Human P2RX7 Protein (Asp356-Tyr595), N-His tagged E.coli N-His Asp356-Tyr595
Human P2RX7-390H Recombinant Human P2RX7 Protein, GST-tagged Wheat Germ GST 1-595
Human P2RX7-3635H Recombinant Human P2RX7 protein, His-tagged E.coli His 382-589 aa
Rat P2RX7-4232R Recombinant Rat P2RX7 Protein Mammalian Cell His
Rat P2RX7-3894R Recombinant Rat P2RX7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat P2RX7-3894R-B Recombinant Rat P2RX7 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish P2RX7-9888Z Recombinant Zebrafish P2RX7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

P2RX7 involved in several pathways and played different roles in them. We selected most pathways P2RX7 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayNOS2A;PPIAA;ORAI1;ATP2B1A;CAMK2G;EDNRB;TACR3;ITPKA;P2RX3A
Neuroactive ligand-receptor interactionGRIN2D;GRM2;GPR156;CRHR2;GRM3;TAAR4;TAAR14L;EDNRBA;HTR5AL

P2RX7 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX7 itself. We selected most functions P2RX7 had, and list some proteins which have the same functions with P2RX7. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAPK8;ATP8B1;SHPRH;ACACB;MAPK11;GK2;SCN8A;PFKFB2A;PRKCDA
extracellular ATP-gated cation channel activityP2RX7;P2RX4A;P2RX3;P2RX4;P2RX1;P2RX4B;P2RX8;P2RX3A;NNR
lipopolysaccharide bindingTLR4;SPON2;KIAA0644;TLR2;PSMB4;CATHL3;SELP;BPIFA2;HSPD1
protein bindingFBXO27;INIP;PRPF40A;ANG;ANGPT1;CDC42EP1;IKBIP;ANKHD1;PHYH
protein homodimerization activityBHLHB9;IL12B;TFAP2B;PDGFRA;FAM109A;DMRTA2;B4GALT1;CBLN1;LRRK2
purinergic nucleotide receptor activityP2RX1;P2RX5;P2RX8;P2RX6;P2RX3A;P2RX7;P2RX4;P2RX4A;P2RX3B
receptor bindingCALCA;Artn;TNFSF13;FYB;Ifnl2;TDGF1;PVRL3B;UCN2;AMH

P2RX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX7.

ABL1; NCK1; GRB2; CASK; TM9SF1; EFNB3

Research Area

Related articles

Bertelli, R; Di Donato, A; et al. LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity. PLOS ONE 9:-(2014).
Furlan-Freguia, C; Marchese, P; et al. P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. JOURNAL OF CLINICAL INVESTIGATION 121:2932-2944(2011).
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