P2RX7
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Official Full Name
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 -
Synonyms
P2RX7;purinergic receptor P2X, ligand-gated ion channel, 7;P2X purinoceptor 7;ATP receptor;P2Z receptor;P2X7 purinoceptor;purinergic receptor P2X7
Recombinant Proteins
- Human
- Rat
- Zebrafish
- E.coli
- HEK293
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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P2RX7-1494H | Recombinant Human P2RX7, GST-tagged | E.coli | Human | GST | C-term-350aa | |
P2RX7-3635H | Recombinant Human P2RX7 protein, His-tagged | E.coli | Human | His | 382-589 aa | |
P2RX7-391H | Recombinant Human P2RX7 Protein, His-tagged | E.coli | Human | His | Ser47~Val334 | |
P2RX7-1219H |
Active Recombinant Human P2RX7 Full Length Transmembrane protein(Nanodisc)
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HEK293 | Human | Non | Full L. |
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P2RX7-4232R | Recombinant Rat P2RX7 Protein | Mammalian Cells | Rat | His |
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P2RX7-9888Z | Recombinant Zebrafish P2RX7 | Mammalian Cells | Zebrafish | His |
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P2RX7-3495HCL | Recombinant Human P2RX7 293 Cell Lysate | HEK293 | Human | Non |
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P2RX7-3894R | Recombinant Rat P2RX7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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P2RX7-3894R-B | Recombinant Rat P2RX7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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P2RX7-390H | Recombinant Human P2RX7 Protein, GST-tagged | Wheat Germ | Human | GST | 1-595 |
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P2RX7-4779H | Recombinant Human P2RX7 Protein (Asp356-Tyr595), N-His tagged | E.coli | Human | His | Asp356-Tyr595 |
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P2RX7-6868HF | Recombinant Full Length Human P2RX7 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 595 amino acids |
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Involved Pathway
P2RX7 involved in several pathways and played different roles in them. We selected most pathways P2RX7 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Neuroactive ligand-receptor interaction | HTR5AL,IL12,PARD3,P2RY1,SCTR,CHRNB3,PTGER2A,F2RL1,GALR3,GABBR2 |
Calcium signaling pathway | MYLK2,PHKA1,GNA15,GRPR,ADRa1A,SLC25A4,PRKCBA,PLCB3,ADRA1BB,CHRM5 |
Protein Function
P2RX7 has several biochemical functions, for example, ATP binding,extracellular ATP-gated cation channel activity,lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX7 itself. We selected most functions P2RX7 had, and list some proteins which have the same functions with P2RX7. You can find most of the proteins on our site.
Function | Related Protein |
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purinergic nucleotide receptor activity | P2RX4,P2RX2,NNR,P2RX3B,P2RX4A,P2RX1,P2RX5,P2RX4B,P2RX8,P2RX3A |
extracellular ATP-gated cation channel activity | P2RX8,P2RX5,P2RX1,NNR,P2RX4A,P2RX6,P2RX2,P2RX3B,P2RX4B,P2RX3A |
lipopolysaccharide binding | PSMB4,BPI,CATHL3,SELP,RNASE7,SPON2,TRIL,LBP,DROSHA,TLR4 |
protein binding | BBS10,ENO1,NDUFB9,CHCHD6,CLINT1,SPRR1A,MYC,HPS6,UBE2E1,C1orf116 |
protein homodimerization activity | SNF8,EIF2AK1,PDXK,S100A16,WWTR1,SDCBP,MAP3K10,MGST1,ASCL1,USH2A |
receptor binding | DAO,CAV1,GSDMA2,HLA-B,CNTFR,DVL3,NRG3,MBL2,REN,PRDX5 |
ATP binding | CDK20,SMARCAD1,CAMK1D,STK17B,TNK1,NARS2,EHD3,SMC4,P2RX3,NDUFA13 |
Interacting Protein
P2RX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX7.
ABL1;NCK1;GRB2;CASK;TM9SF1;EFNB3
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References
- Bertelli, R; Di Donato, A; et al. LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity. PLOS ONE 9:-(2014).
- Furlan-Freguia, C; Marchese, P; et al. P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. JOURNAL OF CLINICAL INVESTIGATION 121:2932-2944(2011).