P2RX7 Protein


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Official Full Name P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 purinoceptor; purinergic receptor P2X7;
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human P2RX7-1494H Recombinant Human P2RX7, GST-tagged E.coli GST
    Rat P2RX7-4232R Recombinant Rat P2RX7 Protein Mammalian Cell His
    Zebrafish P2RX7-9888Z Recombinant Zebrafish P2RX7 Mammalian Cell His
    Human P2RX7-3495HCL Recombinant Human P2RX7 293 Cell Lysate HEK293 N/A
    Human P2RX7-3635H Recombinant Human P2RX7 protein, His-tagged E.coli His
    Human P2RX7-6868HF Recombinant Full Length Human P2RX7 Protein, GST-tagged In Vitro Cell Free System GST
    Human P2RX7-390H Recombinant Human P2RX7 Protein, GST-tagged Wheat Germ GST
    Human P2RX7-391H Recombinant Human P2RX7 Protein, His-tagged E.coli His

    P2RX7 involved in several pathways and played different roles in them. We selected most pathways P2RX7 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway GRIN1B; P2RX5; GRIN1A; AVPR1B; ITPR3; PTGER1; PTGER1A; MYLK3; CACNA1BA; GRM5
    Neuroactive ligand-receptor interaction BRS3; TSHB; NMUR2; P2RY6; TAAR12H; CRHR2; CHRNA2A; LTB4R2; LEP; TAAR64

    P2RX7 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX7 itself. We selected most functions P2RX7 had, and list some proteins which have the same functions with P2RX7. You can find most of the proteins on our site.

    Function Related Protein
    extracellular ATP-gated cation channel activity P2RX8; NNR; P2RX6; P2RX1; P2RX3; P2RX4; P2RX4B; P2RX4A; P2RX3A; P2RX2
    lipopolysaccharide binding BPIFC; RNASE7; CD14; LBP; SPON2; TLR4; CD6; KIAA0644; TREM2; BPI
    protein binding MTAP1A; UCHL5; ZNF3; CHMP2B; KRTAP5-9; VSNL1; CD2; FAM109B; LAMTOR1; PEX11G
    protein homodimerization activity TENM2; KCNH2; CAV2; ERN1; FAP; GPD1L; RCHY1; Trl; WHRN; TRIM5
    purinergic nucleotide receptor activity P2RX3; P2RX7; P2RX4B; P2RX4A; P2RX5; P2RX1; P2RX3A; P2RX8; P2RX4; P2RX2
    receptor binding CXCL1; FGF8A; Artn; PVRL2; NSG1; TESPA1; IFNL3; Fgf15; ANGPTL2; HMGCL

    P2RX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX7.


    Bertelli, R; Di Donato, A; et al. LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity. PLOS ONE 9:-(2014).
    Furlan-Freguia, C; Marchese, P; et al. P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. JOURNAL OF CLINICAL INVESTIGATION 121:2932-2944(2011).

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