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P2RX7

Official Full Name

P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms

P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 purinoceptor; purinergic receptor P2X7;

Type:
Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species :
Human
Rat
Zebrafish

Source :
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	P2RX7-391H	Recombinant Human P2RX7 Protein, His-tagged	E.coli	His	$298.00 / 10ug
Human	P2RX7-1494H	Recombinant Human P2RX7, GST-tagged	E.coli	GST	$319.00 / 25ug
Human	P2RX7-3495HCL	Recombinant Human P2RX7 293 Cell Lysate	HEK293	N/A	Inquiry
Human	P2RX7-390H	Recombinant Human P2RX7 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	P2RX7-3635H	Recombinant Human P2RX7 protein, His-tagged	E.coli	His	$319.00 / 25ug
Rat	P2RX7-3894R	Recombinant Rat P2RX7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Rat	P2RX7-4232R	Recombinant Rat P2RX7 Protein	Mammalian Cell	His	Inquiry
Rat	P2RX7-3894R-B	Recombinant Rat P2RX7 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	P2RX7-9888Z	Recombinant Zebrafish P2RX7	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
P2RX7 Related Articles
P2RX7 Related Research Area

P2RX7 involved in several pathways and played different roles in them. We selected most pathways P2RX7 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Calcium signaling pathway	ERBB4A;TNNC2;PPIF;DRD1B;CAMK2D1;SLC8A1B;SLC25A5;ITPKA;SLC25A4
Neuroactive ligand-receptor interaction	HTR1F;LEPR;S1PR2;MCHR2;NPFFR2;TAAR10C;P2RX3;GRIA4;GALR3

P2RX7 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX7 itself. We selected most functions P2RX7 had, and list some proteins which have the same functions with P2RX7. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	KIFC2;CHD8;MCM2;PKM2;CLCN3;CHD4;CSNK1G3;DHX9;MYHZ1.1
extracellular ATP-gated cation channel activity	P2RX2;P2RX8;P2RX5;P2RX7;P2RX3B;P2RX1;NNR;P2RX6;P2RX4A
lipopolysaccharide binding	SCARB1;P2RX7;TLR2;CATHL3;PSMB4;SELP;BPIFA2;SPON2;BPIFC
protein binding	EDF1;MDFI;C1orf35;ATMIN;ORM1;RUNX2;ZNF502;FAM162A;PDZD11
protein homodimerization activity	LDB1;PTPRO;PRMT8;KLRB1B;TRPM8;PDCD6IP;TRIM5;UGT1A9;ABCD1
purinergic nucleotide receptor activity	P2RX6;P2RX4B;P2RX4A;P2RX1;NNR;P2RX3B;P2RX4;P2RX3A;P2RX8
receptor binding	IL28A;NRG2A;PLAT;FYB;HLA-A;HILPDA;GNB2L1;PCSK1N;CD276

P2RX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX7.

ABL1; NCK1; GRB2; CASK; TM9SF1; EFNB3

Bertelli, R; Di Donato, A; et al. LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity. PLOS ONE 9:-(2014).

Furlan-Freguia, C; Marchese, P; et al. P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. JOURNAL OF CLINICAL INVESTIGATION 121:2932-2944(2011).

Ion Channels and Regulators