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Official Full Name purinergic receptor P2Y, G-protein coupled, 1
Background The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor;subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine;nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to;mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably;to platelet aggregation.
Synonyms P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y purinoceptor 1; P2Y1; ATP receptor; platelet ADP receptor; P2 purinoceptor subtype Y1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human P2RY1-1267HCL Recombinant Human P2RY1 cell lysate N/A
    Mouse P2RY1-12272M Recombinant Mouse P2RY1 Protein Mammalian Cell His
    Rat P2RY1-4233R Recombinant Rat P2RY1 Protein Mammalian Cell His
    Rhesus Macaque P2RY1-3269R Recombinant Rhesus monkey P2RY1 Protein, His-tagged Mammalian Cell His
    Chicken P2RY1-6885C Recombinant Chicken P2RY1 Mammalian Cell His
    Kit-1467 P2RY1 U2OS β-Arrestin GPCR Assay Kit N/A
    Kit-1468 P2RY1 Activated GPCR Internalization Assay Kit N/A

    p2ry1 involved in several pathways and played different roles in them. We selected most pathways p2ry1 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with p2ry1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway PRKD3; PRKD1; RRAS; HGF; PLCB1; PIK3CD; GRIN2A; IGF1; MAPK3; PARD6A
    Neuroactive ligand-receptor interaction SSTR2; RXFP1; NPY6R; NPFFR2; LPAR2; ADORA2AA; GRM8; BDKRB2; KISS1RA; GRIA4B
    Platelet activation FCER1G; GNAQ; PTGIR; F2RL3; PLCB2; PLA2G4F; ITGB3; FERMT3; ITGA2B; PIK3CG

    p2ry1 has several biochemical functions, for example, A1 adenosine receptor binding, ADP binding, ADP-activated adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by p2ry1 itself. We selected most functions p2ry1 had, and list some proteins which have the same functions with p2ry1. You can find most of the proteins on our site.

    Function Related Protein
    A1 adenosine receptor binding P2RY1
    ADP-activated adenosine receptor activity P2RY1
    ATP binding PGS1; PAPSS2A; TRIT1; OXSR1A; CHKA; Abca2; ATP8A1; DAPK3; NAIP1; SRR
    ATP-activated adenosine receptor activity P2RY11; P2RY1
    G-protein coupled purinergic nucleotide receptor activity P2RY10; P2RY2; PTAFR; GPR34B; P2RY13; P2RY6; P2RY8; P2RY11; P2RY1; P2RY14
    protein binding DBC1; TREML1; NFKBIA; LLGL2; SMAD4; DTX2; PLP2; SUPV3L1; VEGFAB; FAM40A
    protein heterodimerization activity CEBPE; HEXA; PEF1; EXT2; BIRC5; MLXIPL; UGT1A2; IL12B; VEGFB; MICU1
    receptor activity ROBO4; FAS; GUCY1B3; PVRL2L; KLRB1F; CD33; CD244; V1RA8; NRXN3; CD200R4
    scaffold protein binding PARK7; KRT5; GRIN2A; HOMER1; KRT8; CIT; TREM2; MDM2; SCN5A; KRT15

    p2ry1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with p2ry1 here. Most of them are supplied by our site. Hope this information will be useful for your research of p2ry1.


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