P2RY1 Protein


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Official Full Name purinergic receptor P2Y, G-protein coupled, 1
Background The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor;subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine;nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to;mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably;to platelet aggregation.
Synonyms P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y purinoceptor 1; P2Y1; ATP receptor; platelet ADP receptor; P2 purinoceptor subtype Y1
    • Species :
    • Bos taurus (Bovine)
    • Cavia porcellus (Guinea pig)
    • Chicken
    • Gallus gallus (Chicken)
    • Homo sapiens (Human)
    • Human
    • Meleagris gallopavo (Wild turkey)
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Source :
    • E.coli expression system
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • His&Flag
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse P2RY1-12272M Recombinant Mouse P2RY1 Protein Mammalian Cell His
    Rat P2RY1-4233R Recombinant Rat P2RY1 Protein Mammalian Cell His
    Rhesus Macaque P2RY1-3269R Recombinant Rhesus monkey P2RY1 Protein, His-tagged Mammalian Cell His
    Chicken P2RY1-6885C Recombinant Chicken P2RY1 Mammalian Cell His
    Human P2RY1-1267HCL Recombinant Human P2RY1 cell lysate N/A
    Human P2RY1-1102HFL Recombinant Human P2RY1 protein, His&Flag-tagged HEK293 His&Flag
    Meleagris gallopavo (Wild turkey) RFL10242MF Recombinant Full Length Meleagris Gallopavo P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Bos taurus (Bovine) RFL11785BF Recombinant Full Length Bovine P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Homo sapiens (Human) RFL16968HF Recombinant Full Length Human P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Cavia porcellus (Guinea pig) RFL22570CF Recombinant Full Length Guinea Pig P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Mus musculus (Mouse) RFL23483MF Recombinant Full Length Mouse P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Rattus norvegicus (Rat) RFL35653RF Recombinant Full Length Rat P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Gallus gallus (Chicken) RFL35980GF Recombinant Full Length Chicken P2Y Purinoceptor 1(P2Ry1) Protein, His-Tagged E.coli expression system His
    Kit-1467 P2RY1 U2OS β-Arrestin GPCR Assay Kit N/A
    Kit-1468 P2RY1 Activated GPCR Internalization Assay Kit N/A

    P2RY1 involved in several pathways and played different roles in them. We selected most pathways P2RY1 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway INS2; PRKCG; FGF9; F2R; MAP2K6; VASP; DOCK4; PIK3CD; ITGAL; RHOA
    Neuroactive ligand-receptor interaction C5AR1; TAAR10; THRB; OPRM1; DRD4-RS; TAAR14E; TACR2; DRD1A; TAAR12B; TAAR7A
    Platelet activation TBXAS1; PIK3R3; MYLK3; PPP1CA; VASP; FGB; MAPK3; GP5; PPP1CC; GUCY1B3

    P2RY1 has several biochemical functions, for example, A1 adenosine receptor binding, ADP binding, ADP-activated adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY1 itself. We selected most functions P2RY1 had, and list some proteins which have the same functions with P2RY1. You can find most of the proteins on our site.

    Function Related Protein
    A1 adenosine receptor binding P2RY1
    ADP binding PKM; MYO9B; MYO6; ATP1A1; HSP104; MIEF1; APAF1; MYO18A; ADCK3; GCLC
    ADP-activated adenosine receptor activity P2RY1
    ATP binding DAPK3; SLC27A5; VARS; MAPK15; CLK3; CCT4; DDX19; PIK3C2B; PFKFB4L; EP400
    ATP-activated adenosine receptor activity P2RY11; P2RY1
    G-protein coupled purinergic nucleotide receptor activity P2RY8; P2RY6; PTAFR; GPR171; P2RY11; P2RY2; GPR34B; P2RY4; P2RY14; P2RY1
    protein binding EXOC8; C10orf96; SRF; EME1; RBM25; Arid4b; CTDP1; AGPAT1; CCDC13; ZBTB5
    protein heterodimerization activity HIST1H2BK; HIST1H3D; IRAK1; TAF9B; H2AFB3; DRD2; RAB3GAP2; TAF13; HSPD1; ADRA1B
    receptor activity RNF139; LYVE1; MED16; NLGN4B; LRP2; APLNR; TRAM1; CSF3R; NOTCH4; ITGB8
    scaffold protein binding DSP; LRP4; MAPK3; TREM1; CACNA1G; MDM2; KCNA5; PARK7; CIT; SHANK3

    P2RY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY1.


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