Recombinant Human P2RY1 cell lysate

• Cat.No.: P2RY1-1267HCL

Specification

• Species: Human
• Tag: Non
• Description: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: P2RY1 purinergic receptor P2Y, G-protein coupled, 1 [ Homo sapiens ]
• Official Symbol: P2RY1
• Synonyms: P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y purinoceptor 1; P2Y1; ATP receptor; platelet ADP receptor; P2 purinoceptor subtype Y1
• Gene ID: 5028
• mRNA Refseq: NM_002563
• Protein Refseq: NP_002554
• MIM: 601167
• UniProt ID: P47900
• Chromosome Location: 3q25.2
• Pathway: ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: A1 adenosine receptor binding; ADP binding; ATP binding; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; protein heterodimerization activity; receptor activity; signal transducer activity