Recombinant Human P2RY1 cell lysate
Cat.No. : | P2RY1-1267HCL |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | P2RY1 purinergic receptor P2Y, G-protein coupled, 1 [ Homo sapiens ] |
Official Symbol : | P2RY1 |
Synonyms : | P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y purinoceptor 1; P2Y1; ATP receptor; platelet ADP receptor; P2 purinoceptor subtype Y1; |
Gene ID : | 5028 |
mRNA Refseq : | NM_002563 |
Protein Refseq : | NP_002554 |
MIM : | 601167 |
UniProt ID : | P47900 |
Chromosome Location : | 3q25.2 |
Pathway : | ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | A1 adenosine receptor binding; ADP binding; ATP binding; G-protein coupled purinergic nucleotide receptor activity; G-protein coupled receptor activity; protein heterodimerization activity; receptor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
P2RY1-0968H | Recombinant Human P2RY1 Protein (T2-L373), Flag tagged | +Inquiry |
P2RY1-6457M | Recombinant Mouse P2RY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
P2RY1-0969H | Recombinant Human P2RY1 Protein (T2-L373), Flag, His tagged | +Inquiry |
P2RY1-3087R | Recombinant Rhesus Macaque P2RY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
P2RY1-3895R | Recombinant Rat P2RY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1468 | P2RY1 Activated GPCR Internalization Assay Kit | +Inquiry |
Kit-1467 | P2RY1 U2OS β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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