PAWR

  • Official Full Name

    PRKC, apoptosis, WT1, regulator

  • Overview

    The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
  • Synonyms

    PAWR; PRKC, apoptosis, WT1, regulator; PRKC apoptosis WT1 regulator protein; par 4; PAR4; WT1-interacting protein; transcriptional repressor PAR4; prostate apoptosis response 4 protein; prostate apoptosis response protein 4; prostate apoptosis response pr;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PAWR-28664TH Recombinant Human PAWR Wheat Germ N/A
Human PAWR-538H Recombinant Human PAWR protein, His & GST-tagged E.coli His/GST
Human PAWR-19H Recombinant Human PAWR, MYC/DDK-tagged HEK293 Myc/DDK
Human PAWR-3420HCL Recombinant Human PAWR 293 Cell Lysate HEK293 N/A
Human PAWR-459H Recombinant Human PAWR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PAWR-359H Recombinant Human PAWR protein, His-tagged E.coli His
Human PAWR-7950HFL Recombinant Full Length Human PAWR, Flag-tagged Mamanlian cells Flag
Mouse PAWR-12389M Recombinant Mouse PAWR Protein Mammalian Cell His
Mouse Pawr-528M Recombinant Mouse Pawr Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse PAWR-6514M-B Recombinant Mouse PAWR Protein Pre-coupled Magnetic Beads HEK293
Mouse PAWR-6514M Recombinant Mouse PAWR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PAWR-4282R Recombinant Rat PAWR Protein Mammalian Cell His
Rat PAWR-3944R-B Recombinant Rat PAWR Protein Pre-coupled Magnetic Beads HEK293
Rat PAWR-3944R Recombinant Rat PAWR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PAWR-1532Z Recombinant Zebrafish PAWR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PAWR Related Research Area

PAWR involved in several pathways and played different roles in them. We selected most pathways PAWR participated on our site, such as Ceramide signaling pathway, Coregulation of Androgen receptor activity, IL-4 signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAWR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ceramide signaling pathwayPAWR;CRADD;CTSD;EGF;DERL3
Coregulation of Androgen receptor activityMAK;TCF4;SVIL;CMTM2A;CTDSP2;CARM1;SNURF;PA2G4;PIAS3
IL-4 signaling PathwaySPI1B;HMGA1-RS1;PAWR;DOK2;ADRBK2;IL4R.1

PAWR has several biochemical functions, for example, actin binding, enzyme binding, leucine zipper domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAWR itself. We selected most functions PAWR had, and list some proteins which have the same functions with PAWR. You can find most of the proteins on our site.

Function Related Protein
actin bindingVPS18;WASB;PHACTR4B;MYH9;TPM3;MYO7B;MYO19;KLHL1;VASP
enzyme bindingCYP2C8;TRIO;LGALS9;PAWR;TRAF2;UGT1A9;KIAA1967;SUDS3;CASP2
leucine zipper domain bindingPAWR;ERC1;AATF;DAPK3;MKL1;NRL;ATF4;CRX;DDIT3
protein bindingATF6;USP5;DYSFIP1;RNF111;WBP11;ABL1;VPS24;DCTN3;TEAD2
protein kinase C bindingMARCKS;PEA15A;PKP2;ADAM9;AKT2;PLEK;FLNA;AKT1;DACT2
protein phosphatase 1 bindingPPP1R9B;KCNQ1;LILRB2;LILRB1;PPP1R15A;SH3RF2;SHOC2;PHACTR3A;PHACTR4
transcription corepressor activityHSF4;HOMEZB;NEUROD2;PEX14;KLF12;CRYM;CDX2;SMYD1;HDAC9

PAWR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAWR here. Most of them are supplied by our site. Hope this information will be useful for your research of PAWR.

HSPA5; Spsb2; SPSB1; Spsb4; SPSB4; SPSB2; Spsb1; Kif23

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