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PITX1

Official Full Name

paired-like homeodomain 1
Overview

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. [provided by RefSeq, Jul 2008]
Synonyms

PITX1; paired-like homeodomain 1; BFT; CCF; POTX; PTX1; LBNBG; pituitary homeobox 1; pituitary homeo box 1; homeobox protein PITX1; pituitary otx-related factor; hindlimb expressed homeobox protein backfoot; hindlimb-expressed homeobox protein backfoot; paired-like homeodomain transcription factor 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
N/A
N
SUMO

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PITX1-28302TH	Recombinant Human PITX1	Wheat Germ	N/A	314 amino acids	Inquiry
Human	PITX1-29536TH	Recombinant Human PITX1	Wheat Germ	N/A	89 amino acids	Inquiry
Human	PITX1-1358HCL	Recombinant Human PITX1 cell lysate		N/A		Inquiry
Human	PITX1-0261H	Recombinant Human PITX1 Protein (Arg90-Gln152), N-SUMO-tagged	E.coli	N-SUMO	Arg90-Gln152	Inquiry
Human	PITX1-372HF	Recombinant Full Length Human PITX1 Protein	In Vitro Cell Free System		314 amino acids	Inquiry
Mouse	PITX1-12849M	Recombinant Mouse PITX1 Protein	Mammalian Cell	His		Inquiry
Mouse	PITX1-6769M	Recombinant Mouse PITX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PITX1-6769M-B	Recombinant Mouse PITX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	PITX1-4476R	Recombinant Rat PITX1 Protein	Mammalian Cell	His		Inquiry
Rat	PITX1-4136R	Recombinant Rat PITX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PITX1-4136R-B	Recombinant Rat PITX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PITX1-3771Z	Recombinant Zebrafish PITX1	Mammalian Cell	His		Inquiry
Chicken	PITX1-4009C	Recombinant Chicken PITX1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PITX1 involved in several pathways and played different roles in them. We selected most pathways PITX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PITX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PITX1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PITX1 itself. We selected most functions PITX1 had, and list some proteins which have the same functions with PITX1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	HOXA7;SREBF2;MXD1;HELT;RELA;MAFA;FOXJ2;NKX2-8;HNRNPK
protein binding	PRSS21;NEU4;PDS5A;ASCL4;STX4;HACE1;CDC25B;RAB27B;SULT4A1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	TFAP2E;GRHL1;MAFA;HMGA2;ARID3B;ONECUT1;NFYC;ZFP750;MITFB
transcriptional activator activity, RNA polymerase II transcription factor binding	MED12;NOTCH1;NFE2L1;FOXH1;WWP2;LMO2;KLF4;JUN;MIXL1

PITX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PITX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PITX1.

RBPMS; DVL3; RHOXF2