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PPIH

  • Official Full Name

    peptidylprolyl isomerase H (cyclophilin H)

  • Overview

    The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
  • Synonyms

    PPIH; peptidylprolyl isomerase H (cyclophilin H); peptidyl prolyl isomerase H (cyclophilin H); peptidyl-prolyl cis-trans isomerase H; cyclophilin H; CYP 20; CYPH; MGC5016; peptidyl prolyl cis trans isomerase H; PPIase h; rotamase H; small nuclear ribonucleoprotein particle specific cyclophilin H; SnuCyp 20; U snRNP associated cyclophilin SunCyp 20; USA CYP; USA CyP SnuCyp 20; EC 5.2.1.8; Peptidylprolyl isomerase H; PPIH_HUMAN; RGD1564921; Small nuclear ribonucleoprotein particle-specific cyclophilin H; U snRNP associated cyclophilin SnuCyp 20; U-snRNP-associated cyclophilin SnuCyp-20; USA-CYP; USACYP; UsnRNP associated cyclophilin SnuCyp20; USA-CyP SnuCyp-20; U-snRNP-associated cyclophilin SunCyp-20; CYP-20; SnuCyp-20;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • HIS
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPIH-111H Recombinant Human Peptidylprolyl Isomerase H E.coli N/A
Human PPIH-181H Recombinant Human PPIH Protein, HIS-tagged E.coli HIS
Human PPIH-30106TH Recombinant Human PPIH E.coli N/A
Human PPIH-219H Recombinant Human PPIH protein, T7-tagged E.coli T7
Human PPIH-30685TH Recombinant Human PPIH, T7 -tagged E.coli T7
Human PPIH-2969HCL Recombinant Human PPIH 293 Cell Lysate HEK293 N/A
Human PPIH-5544H Recombinant Human PPIH Protein (Met1-Met177), N-His tagged E.coli N-His Met1-Met177
Human PPIH-4397H Recombinant Human PPIH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Ppih-5043M Recombinant Mouse Ppih Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque PPIH-3549R Recombinant Rhesus monkey PPIH Protein, His-tagged Mammalian Cell His
Rhesus Macaque PPIH-3367R Recombinant Rhesus Macaque PPIH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PPIH-3367R-B Recombinant Rhesus Macaque PPIH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PPIH-1980Z Recombinant Zebrafish PPIH Mammalian Cell His
Zebrafish PPIH-11421Z Recombinant Zebrafish PPIH Mammalian Cell His
Chicken PPIH-5245C Recombinant Chicken PPIH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PPIH involved in several pathways and played different roles in them. We selected most pathways PPIH participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeALYREF;SRSF2;SRSF5;DHX8;HNRNPC;SNRPC;SART1;DHX38;SNRNP200

PPIH has several biochemical functions, for example, cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIH itself. We selected most functions PPIH had, and list some proteins which have the same functions with PPIH. You can find most of the proteins on our site.

Function Related Protein
cyclosporin A bindingPPID;PPIG;PPIF;PPIH;PPIE;PPIC
peptidyl-prolyl cis-trans isomerase activityFKBP10B;PPIA;PPIL4;TTC9C;PPIFB;FKBP3;FKBPL;FKBP1B;PIN4
protein bindingCD200R3;CPEB4;ECE1;ZFP523;PTRF;ATP7B;EIF4B;KIAA0368;CRLF3
ribonucleoprotein complex bindingPITX2;CKAP5;PES1;PRPF31;ITCH;SECISBP2;PQBP1;WDR12;PES

PPIH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIH here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIH.

PRPF4; N4BP2L2; VCAM1; USP4; SART3; Prpf8; TNIK; USP15; BAG2; PTBP3

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