PRDM14
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Official Full Name
PR domain containing 14
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Overview
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional;regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell;pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in;breast cancer. -
Synonyms
PRDM14; PR domain containing 14; PR domain zinc finger protein 14; PR domain-containing protein 14; PFM11; MGC59730;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- Sf9 Insect Cell
- Flag
- His
- His (Fc)
- Avi
- His|GST
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PRDM14-66H | Recombinant Human PRDM14, FLAG-tagged | Sf9 Insect Cell | Flag |
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| Human | PRDM14-2912H | Recombinant Human PRDM14 Protein, His-tagged | E.coli | His |
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| Human | PRDM14-1486H | Recombinant Human PRDM14 protein, His & GST-tagged | E.coli | His/GST | Glu395~His568 (Accession # Q9GZV8) |
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| Mouse | PRDM14-13314M | Recombinant Mouse PRDM14 Protein | Mammalian Cell | His |
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| Mouse | PRDM14-7066M-B | Recombinant Mouse PRDM14 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | PRDM14-7066M | Recombinant Mouse PRDM14 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | PRDM14-7561Z | Recombinant Zebrafish PRDM14 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- PRDM14 Related Research Area
PRDM14 involved in several pathways and played different roles in them. We selected most pathways PRDM14 participated on our site, such as Developmental Biology, Transcriptional regulation of pluripotent stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDM14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | NRG4;HFE2;HELZ2;BOC;ITSN1;KCNQ3;ACVR1C;TRIO;EFNA1A |
| Transcriptional regulation of pluripotent stem cells | LIN28A;HIF3A;TDGF1;POU5F3;NR5A1;PRDM14;SALL4;FOXD3;NR6A1 |
PRDM14 has several biochemical functions, for example, RNA binding, chromatin DNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDM14 itself. We selected most functions PRDM14 had, and list some proteins which have the same functions with PRDM14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | HNRNPAB;ILF3;CNOT4B;RNASEL4;SPI1;NOL3;PTBP1B;RCAN3;THOC5 |
| chromatin DNA binding | RXRA;PRDM14;H2AFY;PER1;INSM1B;GATA1;RUVBL2;PPARGC1A;ZIC2 |
| metal ion binding | EXO5;COPS5;GLIS1;RXRGB;RXRAA;S100A10A;PRG4B;GATA5;HDAC9 |
| methyltransferase activity | PRDM15;C2orf56;SETD1BA;SMYD2A;NSUN5;PRDM1;TRMT10B;PRMT1;TPMT.1 |
| protein binding | CTRC;BMPR1AA;GPR85;SNAI2;MIA3;ORC4L;RCN2;GPX3;THY1 |
PRDM14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDM14 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDM14.
ATPAF2; HEXIM2; CBFA2T2; Hoxa1; EIF4E2; RAD51D
- Q&As
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