PRDX1 Protein


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Official Full Name peroxiredoxin 1
Background Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1- Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxindependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 – 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
Synonyms PRDX1; peroxiredoxin 1; PAGA; peroxiredoxin-1; NKEFA; NKEF-A; thioredoxin peroxidase 2; proliferation-associated gene A; natural killer-enhancing factor A; proliferation-associated gene protein; natural killer cell-enhancing factor A; thioredoxin-dependen
    • Species :
    • Chicken
    • Cricetulus Griseus
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Yeast
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Prdx1-60M Recombinant Mouse Prdx1 Protein, His-tagged Insect Cell His
    Human PRDX1-134H Recombinant Human Peroxiredoxin 1, His-tagged E.coli His
    Human PRDX1-1939H Recombinant Human PRDX1, GST-tagged E.coli GST
    Human PRDX1-423H Recombinant Human Peroxiredoxin 1, His-tagged Sf9 Insect Cell His
    Mouse Prdx1-2544M Recombinant Mouse Prdx1, His tagged E.coli His
    Mouse Prdx1-8047M Recombinant Mouse Prdx1 protein, His & GST-tagged E.coli His/GST
    Rat PRDX1-4658R Recombinant Rat PRDX1 Protein Mammalian Cell His
    Rhesus Macaque PRDX1-3589R Recombinant Rhesus monkey PRDX1 Protein, His-tagged Mammalian Cell His
    Chicken PRDX1-4683C Recombinant Chicken PRDX1 Mammalian Cell His
    Zebrafish PRDX1-2153Z Recombinant Zebrafish PRDX1 Mammalian Cell His
    Human PRDX1-2882HCL Recombinant Human PRDX1 293 Cell Lysate HEK293 N/A
    Human PRDX1-2883HCL Recombinant Human PRDX1 293 Cell Lysate HEK293 N/A
    Human PRDX1-2430H Recombinant Human PRDX1 Protein (1-199 aa), His-tagged Yeast His
    Human PRDX1-3543H Recombinant Human PRDX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PRDX1-504H Recombinant Human PRDX1 Protein (Met1-Lys199), His-tagged E.coli His
    Human PRDX1-5736H Recombinant Human PRDX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Prdx1-5101M Recombinant Mouse Prdx1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Prdx1-7295M Recombinant Mouse Prdx1 Protein, His-tagged His
    Cricetulus Griseus PRDX1-2033C Recombinant Cricetulus Griseus PRDX1 Protein (2-199 aa), His-tagged E.coli His
    Cricetulus Griseus PRDX1-2679C Recombinant Cricetulus Griseus PRDX1 Protein (2-199 aa), His-tagged Yeast His

    PRDX1 involved in several pathways and played different roles in them. We selected most pathways PRDX1 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    PRDX1 has several biochemical functions, for example, identical protein binding, peroxidase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX1 itself. We selected most functions PRDX1 had, and list some proteins which have the same functions with PRDX1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding PRDX1; PTPRG; BCAT1; STAT6; C; BNIPL; PSMA7; ALDOB; SOX10; PAK2
    peroxidase activity GPX4A; PRDX1; PTGS1; GPX7; GPX4B; PXDN; PTGS2; TPO; PRDX5; GPX8
    poly(A) RNA binding NOP16; PUF60; RBBP6; RPL5B; DDX49; ZCCHC3; NXF3; IMMT; KIAA1967; ANP32A
    protein binding CARM1; HSD17B12; PAFAH1B3; pab1; DDX55; ZFYVE1; DNA2; EXOC7; LSAMP; Fert2
    thioredoxin peroxidase activity PRDX3; PRDX1; PRDX4; PRDX2

    PRDX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX1.

    STK4; PTEN; AR

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