prdx2
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  • Official Full Name
  • peroxiredoxin 2
  • Background
  • This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms
  • PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA; NKEF-B; thiol-specific ant
Cat.#:PRDX2-2247HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human PRDX2 Protein (2-198 aa), His-tagged
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Cat.#:PRDX2-870MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse PRDX2 Protein (Met1-Asn198), His-tagged
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Cat.#:PRDX2-2910HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PRDX2 Protein, MYC/DDK-tagged
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Cat.#:PRDX2-332HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX2 Protein, His-tagged
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Cat.#:PRDX2-333HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX2 Protein, His/GST-tagged
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Cat.#:Prdx2-237MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Sncg Protein, His-tagged, Bioactivity Validated
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Cat.#:Prdx2-334HTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prdx2 Protein, His-tagged
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Cat.#:Prdx2-335RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Prdx2 Protein, His-tagged
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Cat.#:PRDX2-1438HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peroxiredoxin 2, His-tagged
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Cat.#:PRDX2-1152HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PRDX2, His tagged
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Cat.#:PRDX2-142HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peroxiredoxin 2
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Cat.#:PRDX2-29680THTag:His
Source (Host):Species:Human
Product nameRecombinant Human PRDX2, His-tagged
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Cat.#:PRDX2-30464THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX2
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Cat.#:PRDX2-503HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Peroxiredoxin 2, His-tagged
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Cat.#:PRDX2-13323MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRDX2 Protein
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Cat.#:Prdx2-30RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Prdx2 protein, His-tagged
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Cat.#:PRDX2-810CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PRDX2 Protein, His-tagged
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Cat.#:PRDX2-3590RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRDX2 Protein, His-tagged
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Cat.#:PRDX2-598ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PRDX2
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Cat.#:PRDX2-564HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PRDX2 cell lysate
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Involved Pathway

PRDX2 involved in several pathways and played different roles in them. We selected most pathways PRDX2 participated on our site, such as Cellular responses to stress, Detoxification of Reactive Oxygen Species, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular responses to stress
EGLN1B; CBX8; HIST1H1E; ASF1A; PRDX3; ULK1A; KDM6B; TERF1; CBX8B; TXNRD2
Detoxification of Reactive Oxygen Species
TXNRD2; TXN2; PRDX3; TXN; PRDX2; Txn1
Gene Expression
SKIB; JARID2; ZIK1; LSM11; USP9; ZNF10; ZNF133; ZNF71; ZNF23; NR1I3
Generic Transcription Pathway
RORAA; COX5B; MED8; ZNF75D; ZNF10; ZNF706; ZNF615; ZNF614; ZNF263; NRBF2
Selenium Pathway
PRDX2; TXNRD3IT1; SEP15; SELT; PRDX4; ALOX5AP; SAA2; MSRB1; DIO2; SERPINA3
TP53 Regulates Metabolic Genes
SCO1; SURF1; TACO1; FAM36A; COX18; COX14; LRPPRC; PRDX2; COX16; SESN3
Transcriptional Regulation by TP53
COX18; SESN3; COX14; COX16; PRDX2; FAM36A; TACO1

Protein Function

PRDX2 has several biochemical functions, for example, antioxidant activity, thioredoxin peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX2 itself. We selected most functions PRDX2 had, and list some proteins which have the same functions with PRDX2. You can find most of the proteins on our site.
Function
Related Protein
Function antioxidant activity
Related Protein CAT; PRDX2; APOM; KDM3B; FAM213AA; FABP1; S100A9; SEPW1; MT3; UBIAD1
Function thioredoxin peroxidase activity
Related Protein PRDX1; PRDX4; PRDX2; PRDX3

Interacting Protein

PRDX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX2.
BAD; TXN; UTY; A2M; SAT1; CA4; YWHAZ; PRDX4; IFIT5; CDC37; EXOC6; COPS5; ECSIT; RNF32; CD320; NLGN3; MAST1; ere_dna; RNASEH2A