PRDX2

  • Official Full Name

    peroxiredoxin 2

  • Background

    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA; NKEF-B; thiol-specific ant;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Cell & Tissue Lysates
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Insect Cells
    • Mammalian Cell
    • Sf9 Insect Cell
    • Yeast
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • His|GST
    • Myc
    • DDK
    • Myc|DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Cynomolgus Monkey PRDX2-810C Recombinant Cynomolgus PRDX2 Protein, His-tagged Mammalian Cell His
    Cynomolgus Monkey PRDX2-553C-B Recombinant Cynomolgus Monkey PRDX2 Protein Pre-coupled Magnetic Beads HEK293
    Cynomolgus Monkey PRDX2-553C Recombinant Cynomolgus Monkey PRDX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human PRDX2-1438H Active Recombinant Human Peroxiredoxin 2, His-tagged Human His
    Human PRDX2-142H Recombinant Human Peroxiredoxin 2 E.coli N/A
    Human PRDX2-2247H Recombinant Human PRDX2 Protein (2-198 aa), His-tagged Yeast His
    Human PRDX2-1241H Recombinant Human PRDX2 protein, His-tagged Insect Cells His
    Human PRDX2-503H Recombinant Human Peroxiredoxin 2, His-tagged Sf9 Insect Cell His
    Human PRDX2-332H Recombinant Human PRDX2 Protein, His-tagged E.coli His
    Human PRDX2-697H Recombinant Human PRDX2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PRDX2-6209H Recombinant Human PRDX2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PRDX2-2910H Recombinant Human PRDX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PRDX2-336H Recombinant Human PRDX2 protein, GST-tagged E. coli GST
    Human PRDX2-1758H Recombinant Human PRDX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human PRDX2-4027H Recombinant Human PRDX2 protein, His-tagged E.coli His
    Human PRDX2-333H Recombinant Human PRDX2 Protein, His/GST-tagged E.coli His/GST
    Human PRDX2-30464TH Recombinant Human PRDX2 E.coli N/A
    Human PRDX2-1758H-B Recombinant Human PRDX2 Protein Pre-coupled Magnetic Beads HEK293
    Human PRDX2-564HCL Recombinant Human PRDX2 cell lysate Insect Cell N/A
    Human PRDX2-1152H Recombinant Human PRDX2, His tagged Insect Cell His
    Human PRDX2-29680TH Recombinant Human PRDX2, His-tagged His
    Mouse Prdx2-334H Recombinant Mouse Prdx2 Protein, His-tagged E.coli His
    Mouse PRDX2-7070M-B Recombinant Mouse PRDX2 Protein Pre-coupled Magnetic Beads HEK293
    Mouse PRDX2-13323M Recombinant Mouse PRDX2 Protein Mammalian Cell His
    Mouse PRDX2-870M Recombinant Mouse PRDX2 Protein (Met1-Asn198), His-tagged Insect Cell His
    Mouse Prdx2-5102M Recombinant Mouse Prdx2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Prdx2-237M Recombinant Mouse Sncg Protein, His-tagged, Bioactivity Validated E.coli His
    Mouse PRDX2-7070M Recombinant Mouse PRDX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat Prdx2-335R Recombinant Rat Prdx2 Protein, His-tagged E.coli His
    Rat Prdx2-30R Recombinant Rat Prdx2 protein, His-tagged E.coli His
    Rhesus Macaque PRDX2-3590R Recombinant Rhesus monkey PRDX2 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque PRDX2-3408R Recombinant Rhesus Macaque PRDX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque PRDX2-3408R-B Recombinant Rhesus Macaque PRDX2 Protein Pre-coupled Magnetic Beads HEK293
    Zebrafish PRDX2-598Z Recombinant Zebrafish PRDX2 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • PRDX2 Related Research Area

    PRDX2 involved in several pathways and played different roles in them. We selected most pathways PRDX2 participated on our site, such as Cellular responses to stress, Detoxification of Reactive Oxygen Species, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular responses to stressH3F3D;WIPI2;EGLN3;MINK1;IGFBP7;H3F3B.1;TXN;ATG4A;ULK1A
    Detoxification of Reactive Oxygen SpeciesTXNRD2;TXN2;PRDX3;TXN;Txn1;PRDX2
    Gene ExpressionSAP30BP;DARS;NFIA;ZNF253;NFIC;ESRRG;MED15;ZFP36L1;TXNL4A
    Generic Transcription PathwayZNF43;MED13A;ZNF461;ZNF324;ESRRG;ZNF302;MED7;MED6;SURF1
    Selenium PathwayALOX5AP;SELK;CRP;SELT;SAA2-SAA4;PRDX4;DIO2;TXNRD2;SAA4
    TP53 Regulates Metabolic GenesPRDX2;COX14;SESN3;FAM36A;SCO1;TACO1;COX16;SURF1;COX18
    Transcriptional Regulation by TP53FAM36A;COX14;COX16;SESN3;COX18;TACO1;PRDX2

    PRDX2 has several biochemical functions, for example, antioxidant activity, thioredoxin peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX2 itself. We selected most functions PRDX2 had, and list some proteins which have the same functions with PRDX2. You can find most of the proteins on our site.

    Function Related Protein
    antioxidant activityTP53INP1;TRP53INP1;UBIAD1;PRDX5;FAM213AA;FABP1;APOM;SELS;KDM3B
    thioredoxin peroxidase activityPRDX1;PRDX4;PRDX3;PRDX2

    PRDX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX2.

    BAD; TXN; UTY; A2M; SAT1; CA4; YWHAZ; PRDX4; IFIT5; CDC37; EXOC6; COPS5; ECSIT; RNF32; CD320; NLGN3; MAST1; ere_dna; RNASEH2A

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