Active Recombinant Human Peroxiredoxin 2, His-tagged
Cat.No. : | PRDX2-1438H |
Product Overview : | PRDX2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 198 amino acids and having a molecular mass of 21.8 kDa. The PRDX2 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
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Cat. No. : | PRDX2-1438H |
Description : | PRDX2 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX2 takes part as an antioxidant protective role in cells. T-cells. PRDX2 has proliferative effect in cancer development or progression. If PRDX2 protection is insufficient against peroxidases, the DNA damage results in neurological disease such as Alzheimer"s or DNA damage leading to cancer. |
Source : | Human |
Host : | Escherichia Coli. |
Form : | The Peroxiredoxin solution contains 20 mM Tris-HCl pH-8, & 10% glycerol. |
Purity : | Greater than 90.0% as determined by SDS-PAGE. |
Bio-activity : | The specific activity was found to be approximately 200-230 pmole/min/µg. The enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX2 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide that 1 ug of enzyme can reduce at 25°C for 1 minute. |
Physical Appearance : | Sterile Filtered colorless solution. |
Amino acid sequence : | MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN |
Storage : | PRDX2 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | PRDX2 peroxiredoxin 2 [ Homo sapiens ] |
Official Symbol : | PRDX2 |
Synonyms : | PRDX2; peroxiredoxin 2; PRP; TSA; PRX2; TPX1; NKEFB; PRXII; TDPX1; MGC4104; peroxiredoxin-2; torin; NKEF-B; OTTHUMP00000165823; OTTHUMP00000165825; thioredoxin peroxidase 1; thiol-specific antioxidant 1; natural killer-enhancing factor B; thiol-specific antioxidant protein ;natural killer cell-enhancing factor B; thioredoxin-dependent peroxide reductase 1 |
Gene ID : | 7001 |
mRNA Refseq : | NM_005809 |
Protein Refseq : | NP_005800 |
MIM : | 600538 |
UniProt ID : | P32119 |
Chromosome Location : | 19p13 |
Pathway : | Selenium Pathway |
Function : | antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity |
Products Types
◆ Recombinant Protein | ||
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Prdx2-237M | Active Recombinant Mouse Sncg Protein, His-tagged, Bioactivity Validated | +Inquiry |
PRDX2-7070M | Recombinant Mouse PRDX2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRDX2-332H | Recombinant Human PRDX2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRDX2-564HCL | Recombinant Human PRDX2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPRDX2's role in maintaining cellular redox balance implicates it in cancer progression. Modulating PRDX2 levels may offer avenues for developing novel cancer therapies.
As with any targeted therapy, potential side effects need thorough investigation. Modulating PRDX2 levels could impact normal cellular functions, and careful assessment is required.
Some studies suggest that PRDX2 levels may have prognostic value in diseases associated with oxidative stress, providing insights into disease progression.
Yes, PRDX2 is a potential drug target, but challenges include developing specific modulators and understanding the protein's complex regulatory mechanisms.
Research suggests that altered levels of PRDX2 could serve as a biomarker in diseases associated with oxidative stress, offering potential diagnostic applications.
Customer Reviews (3)
Write a reviewI am eager to embark on this scientific journey, empowered by the high-quality PRDX2 protein and the manufacturer's unparalleled assistance.
The manufacturer's prompt and reliable technical support serves as an invaluable resource, reinforcing my confidence in the PRDX2 protein's effectiveness and enabling smooth progress in my experiments.
Its remarkable purity and functional attributes make it an optimal choice for my research, ensuring accurate and reliable outcomes.
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