Recombinant Human PRDX2, His-tagged

• Cat.No.: PRDX2-29680TH
• Product Overview: Recombinant full length Human Peroxiredoxin 2 with N-terminal His tag expressed in a Baculovirus infected Sf9 cell expression system, 22.7 kDa.

Specification

• Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
• Conjugation: HIS
• Biological activity: Specific Activity: 149 pmol/min/μg.3.45 μg of Peroxiredoxin 2 was incubated in 50 mM Hepes (pH 7.0) containing 200 μM NADPH, 3 μM thioredoxin, and 1.5 μM thioredoxin reductase. The reaction mixture was incubated at 30C for 5 min, followed by the addition
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the ahpC/TSA family.Contains 1 thioredoxin domain.

Gene Information

• Gene Name: PRDX2 peroxiredoxin 2 [ Homo sapiens ]
• Official Symbol: PRDX2
• Synonyms: PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA
• Gene ID: 7001
• mRNA Refseq: NM_005809
• Protein Refseq: NP_005800
• MIM: 600538
• Uniprot ID: P32119
• Chromosome Location: 19p13.2
• Pathway: Selenium Pathway, organism-specific biosystem
• Function: antioxidant activity; antioxidant activity; oxidoreductase activity; thioredoxin peroxidase activity; thioredoxin peroxidase activity