PRKCB
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Official Full Name
protein kinase C, beta -
Overview
plays a role in hexosamine biosynthesis pathway induced transcriptional regulation -
Synonyms
Prkcb;protein kinase C, beta;Pkcb;Prkcb1;protein kinase C beta type;PKC-beta;protein kinase C beta I;protein kinase C beta
Recombinant Proteins
- Human
- Mouse
- Rat
- Rabbit
- Rhesus macaque
- E.coli
- Sf9 Cells
- Mammalian Cells
- Insect Cells
- HEK293
- GST
- His
- S
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
PRKCB involved in several pathways and played different roles in them. We selected most pathways PRKCB participated on our site, such as MAPK signaling pathway,ErbB signaling pathway,Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chemokine signaling pathway | SHC1,CCL21B,GNB3,CCL3,CXCL8,GNG8,CXCR6,PRKACA,PIK3CB,GM13304 |
| GABAergic synapse | GNAI1,PRKACA,GNAI2,GLS,GLS2,GABRA3,GABARAP,GNG11,GNG7,GABRA1 |
| VEGF signaling pathway | PTGS2,VEGFAA,AKT2,PIK3R3A,NFATC2,PIK3CA,MAP2K2,AKT2L,MAPK14B,PIK3R3B |
| Influenza A | XPO1,OAS2,IFNB,TBK1,DNAJC3,CASP9,LOC100033925,IRF9,NUP98,ADAR |
| African trypanosomiasis | HBA1,IL12B,TLR9,PLCB4,IL1B,HBA-A2,PLCB1,LAMA4,FAS,HBA2 |
| Rap signaling pathway | KRAS,AKT2,RAC1,MAPK3,Fgf15,FGF22,MRAS,IGF1R,ITGAM,PARD3 |
| Pathways in cancer | FGF16,FZD10,PTGS2,PIK3CA,GNG10,SMAD2,WNT3,BIRC7,ZBTB16,IL-8 |
| Pancreatic secretion | AMY2A4,CPA2,ATP1A2,ATP1B2,CPA1,ATP2A2,ATP2B1,PRSS2,TPCN2,RAB8A |
| Cholinergic synapse | PLCB2,PIK3R3,GNG12,ITPR3,GNAI3,SLC5A7,GNG7,JAK2,CHRM5,FOS |
Protein Function
PRKCB has several biochemical functions, for example, ATP binding,androgen receptor binding,calcium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCB itself. We selected most functions PRKCB had, and list some proteins which have the same functions with PRKCB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | UBE2D4,MAPK8A,MSH4,LMTK3,PIM1,TP53,INSRA,CDK10,FGFR1A,UBE2Q2 |
| histone kinase activity (H3-T6 specific) | PRKCA,PRKCBB |
| chromatin binding | FEZF2,CDC45,NCOA3,PRKCBP1L,RNF168,SMAD6,PATZ1,JUN,POU1F1,PELP1 |
| protein kinase C activity | PRKCHB,PRKCZ,PRKCHA,PRKD1,PRKCD,PRKCE,PKN2,PRKCQ,PKN3,PRKCBA |
| protein kinase C binding | SDPRB,CASQ2,GRK5,PDLIM5,MARCKS,TRPV4,PRKCSH,AKT1,ADAM9,LDB3 |
| ligand-dependent nuclear receptor transcription coactivator activity | MED17,PPARG,THRAP3,PKN1,NCOA2,SLC30A9,AASS,KDM1A,MED30,USP22 |
| protein serine/threonine kinase activity | TP53RK,MAP3K11,STK17B,RPS6KA5,GAK,RPS6KB2,ACVR2AA,MOK,LRRK2,NUAK1 |
| zinc ion binding | APOBEC4,CBLC,TRIM39,CAR5A,UQCRC2,TRIM43B,TRIM38,CECR1,RPH3A,UBR7 |
| histone binding | COPRS,USP49,HIST4H4,HIST2H4A,RBBP4,ELP2,MCM2,CD1D,HIST1H4H,TBL1XR1 |
Interacting Protein
PRKCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCB.
TINF2;N/A;Glrb;PRL1;IKBKB;CHUK;LYN;HSP90AB1;GSK3B;GNB2L1;SHCBP1;PAG1;AKT1;TERF1;amn;bosutinib;bisindolylmaleimide iii;imatinib
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