PRKCB
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Official Full Name
protein kinase C, beta
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Overview
plays a role in hexosamine biosynthesis pathway induced transcriptional regulation -
Synonyms
Prkcb; protein kinase C, beta; Pkcb; Prkcb1; protein kinase C beta type; PKC-beta; protein kinase C beta I; protein kinase C beta;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Human
- Mouse
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- Rat
- Rhesus Macaque
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- Mammalian cells
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- C
- Myc
- DDK
- Flag
- GST
- His
- His (Fc)
- Avi
- His|S
- N/A
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
PRKCB involved in several pathways and played different roles in them. We selected most pathways PRKCB participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | MAP4K2;RPS6KA6;MRAS;CACNA1SB;IL1A;PPM1AB;MAP3K14;ACVR1C;RAC3A |
| ErbB signaling pathway | PRKCG;ABL1;PAK3;RAF1B;PLCG2;GRB2A;NCK2B;SHC4;STAT5A |
| Ras signaling pathway | LAT;FGF3;FGF17;GRB2;INS;VEGFA;ETS1;CALML3;FGF10 |
| Rap signaling pathway | DOCK4;PRKCI;CDC42;PARD6A;INS;FGFR2;PARD3;FGFR3;Itgam&Itgb2 |
| Calcium signaling pathway | CYSLTR2;AGTR1A;PHKA2;ATP2A2;ERBB3B;PPIF;ADRB1;PTGER1;P2RX4B |
| Chemokine signaling pathway | PRKCD;AKT1;ADRBK1;WASL;CCL4L1;VAV3;CCL28;PF4;NFKB1 |
| NF-kappa B signaling pathway | LTB;ZAP70;IRAK4;LAT;TNFSF11;TRAF6;DDX58;PIDD1;CCL4L1 |
| HIF- signaling pathway | NOX1;MAPK3;HK3;HK2;PDHA1;ENO1;CAMK2A;GM5506;RBX1 |
| Phosphatidylinositol signaling system | INPP5KA;IMPA1;PRKCBB;PIP5K2;IMPA2;PTEN;PIP5K1AA;DGKE;PLCD1B |
| Sphingolipid signaling pathway | RELA;PIK3R2;AKT2;MAPK1;PLCB2;PRKCE;RAF1;PPP2CB;DEGS1 |
| mTOR signaling pathway | EIF4E2;AKT2;IRS1;PIK3R5;RRAGCB;RPS6KB1;PIK3R3;VEGFA;MAPK3 |
| Vascular smooth muscle contraction | PRKACAB;CACNA1D;ACTA2;MAP2K2B;CALM3B;MAPK3;ARHGEF12;CALM3;RAF1A |
| Wnt signaling pathway | FZD7B;WNT3;WNT6;FZD8;PRKACB;DAAM1;CAMK2D;NKD2B;TCF7L1A |
| VEGF signaling pathway | RAC1A;PLA2G4D;PPP3R1B;RAC3;MAP2K2B;MAPK14A;CDC42L2;PPP3R2;RAC1 |
| Focal adhesion | COL11A1A;ACTG1;Reln;BAD;LAMA4;COL6A2;PIK3R3B;PAK7;HRASB |
| Tight junction | PRKCQ;ACTN3A;EPB41L2;PPP2R2A;ACTN2B;CLDN8;MPP5A;GNAI2;RRAS2 |
| Gap junction | PDGFRB;TUBA4A;GRM5;GNA11B;TUBA8;GRB2A;TJP1;TUBA7L;GUCY1A3 |
| Natural killer cell mediated cytotoxicity | CD247;PIK3CB;ULBP2;KLRC4-KLRK1;SHC2;IFNA13;SH3BP2;Ifna11;IFNA7 |
| B cell receptor signaling pathway | TTC6;MAP2K1;VAV3;CDK7;RAF1;IKBKB;CARD11;AKT1;GSK3AB |
| Fc gamma R-mediated phagocytosis | BIN1;SCIN;PPAP2A;PRKCE;CDC42;ASAP1;PLA2G4A;FCGR2A;VAV3 |
| Leukocyte transendothelial migration | NCF1;JAM2;PIK3CD;VASP;ARHGAP35;VCL;CD99;CLDN1;CLDN8 |
| Circadian entrainment | KCNJ6;AKR1C1;GNAQ;PRKG1;GRIN2D;CAMK2G;GRIA1;PLCB3;PLCB2 |
| Long-term potentiation | RAP1B;GRIA1;PPP3CC;GRM5;CAMK2A;PRKCB;ITPR1;RAP1A;RPS6KA3 |
| Retrograde endocannabinoid signaling | GNG5;PLCB4;SLC17A8;RIMS1;ITPR3;GABRB3;MAPK11;GABRR1;GRIA3 |
| Glutamatergic synapse | GRIK2;PRKACG;ITPR1;GRIK5;GNGT2;GNAI3;SLC38A3;GRM4;PPP3CA |
| Cholinergic synapse | CREB3L2;CHRNA7;MAPK1;CAMK2G;ITPR3;HRAS;SLC5A7;PIK3CD;GNB2 |
| Serotonergic synapse | GNG2;GNG11;GNGT1;ALOX15;CYP4X1;HTR1A;ALOX5;GNAS;HTR3B |
| GABAergic synapse | GABRQ;GABRA5;SLC38A5;GNAI1;GABRA4;GAD2;GABRA3;GNG10;GABRR1 |
| Dopaminergic synapse | GNAO1;PPP2R1A;DRD1;PRKACA;KCNJ6;CALM3;CREB3;TH;PPP1CA |
| Long-term depression | GRIA3;KRAS;GNAS;PLCB1;GNA11;PLA2G4A;PRKCB;GNAI2;GNAI3 |
| Inflammatory mediator regulation of TRP channels | MAPK9;PTGER4;HTR2B;CYP2C55;PRKCB;HTR2A;Adcy4;MAPK11;TRPV1 |
| Insulin secretion | KCNMB3;SLC2A1;CAMK2D;FXYD2;STX1A;GNAS;ATP1A2;KCNMA1;PRKCG |
| GnRH signaling pathway | MAPK1;RAF1B;MAP2K3;CDC42L2;KRAS;PRKCB;CDC42L;PRKACG;MAPK8 |
| Melanogenesis | PLCB2;PRKACAA;WNT2BA;KITLG;WNT5A;GNAO1;CALM2;PRKACG;FZD8A |
| Thyroid hormone synthesis | PRKCA;GPX5;CREB3L3;GSR;GPX2;PRKACG;ATP1A4;GPX8;PLCB2 |
| Thyroid hormone signaling pathway | TRP53;HDAC3;SRC;KRAS;NRAS;BAD;RAF1;ITGAV;PLCE1 |
| Oxytocin signaling pathway | PIK3CA;MYLK4;CACNG1;CACNG4;PLA2G4A;MAPK7;CALM2;MYLK3;GUCY1A3 |
| Aldosterone synthesis and secretion | CREB3L4;ADCY7;PRKCG;CAMK1G;ATF6B;PLCB1;PRKACG;PRKCB;LIPE |
| Insulin resistance | PTPN11A;RPS6KB2;RPS6KB1B;MLXIPL;SLC2A4;RPS6KA3;PPP1CC;SLC27A1A;PIK3CB |
| Aldosterone-regulated sodium reabsorption | PRKCG;KCNJ1;ATP1B1;MAPK1;ATP1B2;ATP1B3;PIK3CD;FXYD2;PIK3R3 |
| Endocrine and other factor-regulated calcium reabsorption | KLK2;KLK1B5;KLK1B22;PRKCB;DNM3;KL;ESR1;ATP1A1;ATP1B3 |
| Salivary secretion | ATP1A4;TRPV6;PRKCB;PRB1;PRKG2;PLCB2;ATP2B1;GNAQ;PRH2 |
| Gastric acid secretion | CAMK2D;MYLK;HRH2;SST;KCNJ15;KCNE2;SSTR2;CCKBR;ATP1B3 |
| Pancreatic secretion | PLA2G2D;SLC26A3;PLA2G2E;FXYD2;CPB2;CLCA3;CPB1;PRSS2;SLC9A1 |
| Carbohydrate digestion and absorption | HK1;PRKCB;SI;AMY2A2;AKT1;SLC2A2;HK3;AMY2A4;PIK3R3 |
| Leishmaniasis | IL4;MAP3K7;ITGB1;NFKB1;HLA-DOA;FCGR3A;NFKBIA;FCGR1A;MAPK12 |
| African trypanosomiasis | IDO1;PLCB4;THOP1;IFNG;HBA-A2;PLCB2;ICAM1;HBA1;IL10 |
| Amoebiasis | CXCL8;TGFB3;LAMB1;PIK3CD;SERPINB1;SERPINB3;COL4A4;ARG1;COL5A1 |
| Hepatitis B | PIK3R1;DDB2;IKBKB;IFNA14;IKBKE;Fasl;MAPK3;IFNA17;PIK3CG |
| Influenza A | TNFRSF10C;BLB1;NFKBIB;CCL5;VDAC1;RAF1;TNFRSF1A;TNFRSF10B;IL12B |
| Pathways in cancer | AGTR1B;PTGER1;ARNT;NKX3-1;FGFR2;SKP2;CTBP2;MECOM;PIK3CG |
| Proteoglycans in cancer | HCLS1;CD63;ACTG1;TIMP3;MAPK1;SDC4;FZD8;IL12B;DROSHA |
| MicroRNAs in cancer | PDGFRA;DNMT3B;TNR;SOCS1;VEGFA;DICER1;STAT3;MMP9;APC |
| Glioma | MAPK3;MAPK1;CALM3;IGF1R;ARAF;TRP53;PIK3R3;SHC2;PDGFRA |
| Non-small cell lung cancer | RB1;ALK;GRB2;PIK3CB;RASSF5;BAD;CASP9;SOS1;NRAS |
| Choline metabolism in cancer | WASF3;SP1;PCYT1A;PIK3R5;RPS6KB1;PDGFA;WAS;MAPK8;PPAP2A |
PRKCB has several biochemical functions, for example, ATP binding, androgen receptor binding, calcium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCB itself. We selected most functions PRKCB had, and list some proteins which have the same functions with PRKCB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | NLRP5;CARS;VPS4A;SMARCAD1;ENPP1;ATP7B;MYO1G;FRK;NME1 |
| androgen receptor binding | TGFB1I1;NCOA3;CALR;NRIP1;EP300;DDX5;KDM3A;PIAS1;CDK7 |
| calcium channel regulator activity | SGK2;NPY;PLN;CACNA2D1A;TMEM110;NRXN1;TSPAN13A;CACNA2D2;CRISP1 |
| chromatin binding | TAF2;EZH1;PDX1;Trl;TLE1;ERCC6;UXT;SIRT6;ASF1A |
| histone binding | HIST1H4A;HIST2H3C1;NPM2;NCAPD2;USP16;ANP32B;ATAD2;HIST2H4;HIST1H4D |
| histone kinase activity (H3-T6 specific) | PRKCA;PRKCB;PRKCBB |
| ligand-dependent nuclear receptor transcription coactivator activity | USP22;ENY2;CALCOCO1;PKN1;KDM1A;ZMIZ2;PPRC1;ACTN4;LRP2BP |
| protein binding | TMEM8A;TNFRSF14;PIP5K1B;SSTR3;FNIP1;RARG;KRTAP10-4;TH1L;RDM1 |
| protein kinase C activity | PRKCE;PRKCQ;PRKCZ;PKN3;PRKCBA;PRKCB;PRKCDA;PRKD1;PRKCD |
| protein kinase C binding | HDAC7A;AKT2;GRK5;DACT2;TOP2B;TRPV4;HSPB1;PEA15A;DACT1 |
| protein serine/threonine kinase activity | PDIK1L;PRKCBB;RIOK3;TAOK3;NEK7;TAOK2;RPS6KC1;PRKCBA;ROCK2A |
| zinc ion binding | RFFL;PHF23A;RTN4IP1;LNX2B;NR1D4B;RNF31;NR2F6;TRIM8A;PHRF1 |
PRKCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCB.
TINF2; N/A; Glrb; PRL1; IKBKB; CHUK; LYN; HSP90AB1; GSK3B; GNB2L1; SHCBP1; PAG1; AKT1; TERF1; amn; bosutinib; bisindolylmaleimide iii; imatinib
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