Recombinant Human Protein Kinase C, Beta, GST-tagged

• Cat.No.: PRKCB-1302H
• Product Overview: Recombinanthuman full length PRKCB with N-terminal GST tag was expressed in Sf9 insectcells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: PRKCB isa member of the protein kinase C (PKC) family of serine- andthreonine-specific protein kinases that can be activated by calcium andsecond messenger diacylglycerol and phosphorylate a wide variety of proteintargets known to be involved in diverse cellular signaling pathways. PRKCBhas been reported to be involved in many different cellular functions such asB-cell activation, apoptosis induction, endothelial cell proliferation, andintestinal sugar absorption.
• Form: Liquid in50 mM Tris-HCl, pH 7.5 + 150 mM NaCl + 0.25 mM DTT + 0.1 mM EGTA + 0.1 mMEDTA + 0.1 mM PMSF + 25% glycerol.
• Molecular Weight: ~ 150 kDa
• Purity: > 90% asdetermined by densitometry
• Concentration: 0.1 mg/ml
• Specific Activity: 368nmol/min/mg
• Storage: Stablefor 1 year in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PRKCB
• Function: nucleotide binding; proteinbinding; protein kinase activity; protein serine/threonine kinase activity; zincion binding; metal ion binding; histone kinase activity (H3-T6 specific); enzymebinding; ATP binding
• Full Length: Full L.

Gene Information

• Gene Name: PRKCB protein kinase C, beta [ Homosapiens ]
• Synonyms: PRKCB; proteinkinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; proteinkinase C, beta 1; OTTHUMP00000162377; OTTHUMP00000162378; Protein kinase C, betatype; PKC-B;EC 2.7.11.13; protein kinase C, beta 1 polypeptide
• Gene ID: 5579
• mRNA Refseq: NM_002738
• Protein Refseq: NP_002729
• MIM: 176970
• UniProt ID: P05771
• Chromosome Location: 16p12
• Pathway: African trypanosomiasis; Aldosterone-regulatedsodium reabsorption; Alpha6-Beta4 Integrin Signaling Pathway; Amoebiasis; Ca-dependentevents; CaM pathway; Calcium Regulation in the Cardiac Cell; Calciumsignaling pathway; Calmodulin induced events; Canonical NF-kappaB pathway; Cholinergicsynapse; DAG and IP3 signaling; Disinhibition of SNARE formation; Dopaminergicsynapse