psmd10

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psmd10

Official Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Background This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Synonyms PSMD10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; 26S proteasome non-ATPase regulatory subunit 10; gankyrin; p28; ankyrin repeat protein; 26S proteasome regulatory subunit p28; hepatocellular carcinoma-associated protein p28-II; p28(GAN
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMD10-1136H Recombinant Human PSMD10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PSMD10-1502H Recombinant Human PSMD10 protein, His & T7-tagged E.coli His/T7
    Human PSMD10-2026H Recombinant Human PSMD10, GST-tagged E.coli GST
    Human PSMD10-2742H Recombinant Human PSMD10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PSMD10-2755HCL Recombinant Human PSMD10 293 Cell Lysate HEK293 N/A
    Human PSMD10-2756HCL Recombinant Human PSMD10 293 Cell Lysate HEK293 N/A
    Human PSMD10-358H Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 E.coli N/A
    Human PSMD10-6927H Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 E.coli N/A
    Mouse Psmd10-5189M Recombinant Mouse Psmd10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat PSMD10-4785R Recombinant Rat PSMD10 Protein Mammalian Cell His
    Rhesus Macaque PSMD10-3668R Recombinant Rhesus monkey PSMD10 Protein, His-tagged Mammalian Cell His
    Chicken PSMD10-5240C Recombinant Chicken PSMD10 Mammalian Cell His
    Zebrafish PSMD10-11769Z Recombinant Zebrafish PSMD10 Mammalian Cell His

    psmd10 involved in several pathways and played different roles in them. We selected most pathways psmd10 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with psmd10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    APC/C-mediated degradation of cell cycle proteins PSMD14; CDK2; PSME3; UBE2C; PSMA8; AURKB; PSMD10; PSMD9; PSMD5; ANAPC10
    APC/C:Cdc20 mediated degradation of Securin PSMA8; ANAPC10; PSMD14; PSME3; PSMD10; UBE2C; PSMD5; PSMD9
    APC/C:Cdc20 mediated degradation of mitotic proteins PSMD14; PSMD5; ANAPC10; PSMD9; NEK2; PSMA8; UBE2C; PSME3; PSMD10
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 PSMD10; PSMD14; PSMA8; UBE2C; PSME3; ANAPC10; AURKB; PSMD9; PSMD5
    APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint ANAPC10; NEK2; PSMD9; PSMA8; PSMD14; PSMD10; UBE2C; PSME3; PSMD5
    ARMS-mediated activation IL17RD; FGFR1B; JAK3; NRG4; PEBP1; CSK; SPNA1; PSMA8; SLC14A2; DUSP4
    AUF1 (hnRNP D0) binds and destabilizes mRNA PSMD10; PSMD5; PSMA8; PSME3; EIF4G1; PSMD9; HNRNPD; PSMD14
    Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins PSMD14; UBE2C; NEK2; PSMD9; ANAPC10; PSMD10; PSMD5; PSMA8; PSME3

    psmd10 has several biochemical functions, for example, protein binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by psmd10 itself. We selected most functions psmd10 had, and list some proteins which have the same functions with psmd10. You can find most of the proteins on our site.

    Function Related Protein
    protein binding VDAC2; ROPN1; MYL2; ZNF385C; PKP2; MEIOB; NOL3; NOTCH3; ATXN7L3; STK36
    transcription factor binding FOXA1; KEAP1B; PER1; GTF2F1; PPRC1; ZFPM1; CEBPG; GATA3; NLRP3; IFI16

    psmd10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with psmd10 here. Most of them are supplied by our site. Hope this information will be useful for your research of psmd10.

    PSMC4; PSMC1; PSMD7

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