PTGDR

  • Official Full Name

    prostaglandin D2 receptor (DP)

  • Overview

    The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+.Knockout studies in mice suggest that the ligand of this receptor,prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
  • Synonyms

    PTGDR; prostaglandin D2 receptor (DP); prostaglandin D2 receptor; DP; DP1; PTGDR1; AS 1; AS1; ASRT 1; ASRT1; MGC49004; OTTHUMP00000178986; PD2R_HUMAN; PGD receptor; PGD2 receptor; Prostanoid DP receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PTGDR-31204TH Recombinant Human PTGDR Wheat Germ N/A 359 amino acids
Human PTGDR-2719HCL Recombinant Human PTGDR 293 Cell Lysate HEK293 N/A
Human PTGDR-411HF Recombinant Full Length Human PTGDR Protein In Vitro Cell Free System 359 amino acids
Mouse PTGDR-13634M Recombinant Mouse PTGDR Protein Mammalian Cell His
Mouse PTGDR-7251M Recombinant Mouse PTGDR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PTGDR-7251M-B Recombinant Mouse PTGDR Protein Pre-coupled Magnetic Beads HEK293
Rat PTGDR-4802R Recombinant Rat PTGDR Protein Mammalian Cell His
Rat PTGDR-4461R-B Recombinant Rat PTGDR Protein Pre-coupled Magnetic Beads HEK293
Rat PTGDR-4461R Recombinant Rat PTGDR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL31280BF Recombinant Full Length Bovine Prostaglandin D2 Receptor(Ptgdr) Protein, His-Tagged E.coli expression system His Full Length (1-361)
Homo sapiens (Human) RFL33804HF Recombinant Full Length Human Prostaglandin D2 Receptor(Ptgdr) Protein, His-Tagged E.coli expression system His Full Length (1-359)
Mus musculus (Mouse) RFL10774MF Recombinant Full Length Mouse Prostaglandin D2 Receptor(Ptgdr) Protein, His-Tagged E.coli expression system His Full Length (1-357)
Rattus norvegicus (Rat) RFL10942RF Recombinant Full Length Rat Prostaglandin D2 Receptor(Ptgdr) Protein, His-Tagged E.coli expression system His Full Length (1-357)
Kit-1485 cAMP PTGDR CHO-K1 GPCR Assay Kit N/A
Kit-1080 Ascorbic Acid Colorimetric/Fluorometric Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PTGDR involved in several pathways and played different roles in them. We selected most pathways PTGDR participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTGDR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionLHB;F2RL1.2;CHRNA9;PTGFR;BDKRB1;P2RY10;PTH1RB;ADORA2AB;ADRA2DB

PTGDR has several biochemical functions, for example, prostaglandin D receptor activity, prostaglandin J receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTGDR itself. We selected most functions PTGDR had, and list some proteins which have the same functions with PTGDR. You can find most of the proteins on our site.

Function Related Protein
prostaglandin D receptor activityPTGDR2;PTGDR
prostaglandin J receptor activityPTGDR2;PTGDR
protein bindingKIAA1267;INPPL1;SPRYD7;CDCA8;LURAP1;FGFR1;KLRB1B;ORC2L;FBXL12

PTGDR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTGDR here. Most of them are supplied by our site. Hope this information will be useful for your research of PTGDR.

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