|Official Full Name||retinoic acid early transcript 1E|
|Background||This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||RAET1E; retinoic acid early transcript 1E; NKG2D ligand 4; bA350J20.7; LETAL; ULBP4; Lymphocyte effector toxicity activation ligand; MGC125308; MGC125309; N2DL-4; N2DL4; NKG2D ligand 4 precursor; NKG2DL4; RAE-1-like transcript 4; RAET1E2; RL-4; OTTHUMP00000017403; OTTHUMP00000017404; OTTHUMP00000229731|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
raet1e involved in several pathways and played different roles in them. We selected most pathways raet1e participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with raet1e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||KLRF1; UBE2F; RNF123; UBE2V1; AMICA1; CD300LB; SPSB1; HLA-DQB2; CRTAM; TRIM41|
|Immune System||BTR09; IRF6; DCTN3; CD300LF; DEFB104A; S100B; KIF4; CTSD; ERAP2; RIPK3|
|Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell||CD160; SIGLEC7; AF251705; CD200R1; SH2D1B; SIGLEC8; LILRA1; LILRB1; Mill2; ICAM4|
|Natural killer cell mediated cytotoxicity||ICAM1; IFNA8; KLRC4-KLRK1; ITGB2; NCR2; MAP2K2; PRKCB; LCP2; KLRD1; SH3BP2|
raet1e has several biochemical functions, for example, natural killer cell lectin-like receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by raet1e itself. We selected most functions raet1e had, and list some proteins which have the same functions with raet1e. You can find most of the proteins on our site.
|natural killer cell lectin-like receptor binding||CLEC2H; MICB; RAET1G; Raet1a; HLA-E; ULBP3; RAET1E; ULBP2; RAET1L; ULBP1|
raet1e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with raet1e here. Most of them are supplied by our site. Hope this information will be useful for your research of raet1e.