Active Recombinant Mouse Raet1e Protein, Fc tagged

• Cat.No.: Raet1e-01M
• Product Overview: Recombinant Mouse Rae-1 epsilon (Leu29 - Ser229) protein with Human IgG1 (Pro100 - Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.

Specification

• Species: Mouse
• Source: Mouse myeloma cell line
• Tag: Fc
• Protein Length: 29-229 aa
• Description: Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within T cell mediated cytotoxicity. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in embryo; embryo endoderm; and midgut. Orthologous to human RAET1G (retinoic acid early transcript 1G) and RAET1L (retinoic acid early transcript 1L).
• Source: Mouse myeloma cell line
• Species: Mouse
• Tag: C-Fc
• Form: Disulfide-linked homodimer
• Molecular Weight: 49.3 kDa (monomer)
• Bio-Activity: Measured by the ability of the protein to bind to immobilized rmNKG2D/Fc Chimera in a functional ELISA.
• N-terminal Sequence Analysis: Leu29
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 90% by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Shipping: The product is shipped at ambient temperature.
• Reference: 1. Zou, Z. et al. (1996) J. Biochem (Tokyo) 119:319.
  2. Diefenbach, A. et al. (2000) Nature Immunol. 1:119.
  3. Cerwenka, A. et al. (2000) Immunity 12:721.

Gene Information

• Gene Name: Raet1e retinoic acid early transcript 1E [ Mus musculus (house mouse) ]
• Official Symbol: Raet1e
• Synonyms: RAET1E; retinoic acid early transcript 1E; retinoic acid early-inducible protein 1-epsilon; RAE-1-epsilon; Rae-1 epsilon
• Gene ID: 379043
• mRNA Refseq: NM_198193
• Protein Refseq: NP_937836
• UniProt ID: Q9CZQ6