Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Rcan2

  • Official Full Name

    regulator of calcineurin 2

  • Overview

    This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms

    RCAN2; regulator of calcineurin 2; Down syndrome critical region gene 1 like 1 , DSCR1L1; calcipressin-2; ZAKI 4; Calcipressin 2; CSP2; Down syndrome candidate region 1-like 1; Down syndrome critical region gene 1 like 1 protein; MCIP2; Myocyte enriched calcineurin interacting protein 2; Myocyte-enriched calcineurin-interacting protein 2; RCAN2_HUMAN; RCN2; Thyroid hormone responsive protein ZAKI4; Thyroid hormone-responsive protein ZAKI-4; ZAKI4; Down syndrome critical region gene 1-like 1; thyroid hormone-responsive (skin fibroblasts); ZAKI-4; DSCR1L1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RCAN2-28376TH Recombinant Human RCAN2, His-tagged E.coli His 197 amino acids
Human RCAN2-4031H Recombinant Human RCAN2 Protein, GST-tagged Wheat Germ GST
Human RCAN2-6859H Recombinant Human Regulator Of Calcineurin 2, His-tagged E.coli His 1-197aa
Human RCAN2-4750H Recombinant Human Regulator Of Calcineurin 2, His-tagged Human His
Human Rcan2-1562M Recombinant Human Regulator Of Calcineurin 2, His-tagged E.coli His
Human RCAN2-2449HCL Recombinant Human RCAN2 293 Cell Lysate HEK293 N/A
Human RCAN2-713H Recombinant Human RCAN2 Protein, GST/His-tagged E.coli GST/His
Human RCAN2-4710HF Recombinant Full Length Human RCAN2 Protein, GST-tagged In Vitro Cell Free System GST 225 amino acids
Rat RCAN2-4973R Recombinant Rat RCAN2 Protein Mammalian Cell His
Rat RCAN2-4632R Recombinant Rat RCAN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RCAN2-4632R-B Recombinant Rat RCAN2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RCAN2-12828Z Recombinant Zebrafish RCAN2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Rcan2 Related Articles

Rcan2 involved in several pathways and played different roles in them. We selected most pathways Rcan2 participated on our site, such as Calcium signaling in the CD4+ TCR pathway, Role of Calcineurin-dependent NFAT signaling in lymphocytes, Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rcan2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling in the CD4+ TCR pathwayBATF3;RCAN1;POU2F1;CHP;CSF2;AKAP5;JUNB;RCAN2;FKBP1A
Role of Calcineurin-dependent NFAT signaling in lymphocytesFKBP8;RCAN1;RCAN2;CHP
Thyroid hormone signaling pathwayHDAC1;PLCZ1;ACTB;ATP2A2;ATP1B1;TBC1D4;RCAN1;RAF1;PIK3CG

Rcan2 has several biochemical functions, for example, calcium-dependent protein serine/threonine phosphatase regulator activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Rcan2 itself. We selected most functions Rcan2 had, and list some proteins which have the same functions with Rcan2. You can find most of the proteins on our site.

Function Related Protein
calcium-dependent protein serine/threonine phosphatase regulator activityRCAN2;RCAN1;RCAN1A;RCAN3
nucleotide bindingARL4CB;PCXB;PFKMB;RHOT1A;SF3B14;SRSF2A;RBM5;RNPS1;DAZAP1

Rcan2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rcan2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Rcan2.

TCEB1

Qin, WP; Pan, JP; et al. Anabolic steroids activate calcineurin-NFAT signaling and thereby increase myotube size and reduce denervation atrophy. MOLECULAR AND CELLULAR ENDOCRINOLOGY 399:336-345(2015).
Skoda, G; Kerekes, A; et al. Examination of a regulatory SNP of bovine RCAN2 gene in transgenic mouse models. TRANSGENIC RESEARCH 23:889-889(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Rcan2 Products

Required fields are marked with *

My Review for All Rcan2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends