RCOR1
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Official Full Name
REST corepressor 1
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Overview
This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011] -
Synonyms
RCOR1; REST corepressor 1; RCOR; COREST;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | RCOR1-1852H | Recombinant Human REST Corepressor 1, His-tagged | E.coli | His |
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| Human | RCOR1-71H | Recombinant Human RCOR1 protein, His-tagged | E.coli | His | 294-485 |
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| Human | RCOR1-73H | Recombinant Human RCOR1 protein, GST-tagged | Wheat Germ | GST |
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| Human | RCOR1-301383H | Recombinant Human RCOR1 protein, GST-tagged | E.coli | GST | Met245-Pro310 |
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| Mouse | RCOR1-14038M | Recombinant Mouse RCOR1 Protein | Mammalian Cell | His |
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| Mouse | RCOR1-7502M-B | Recombinant Mouse RCOR1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | RCOR1-7502M | Recombinant Mouse RCOR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | RCOR1-4984Z | Recombinant Zebrafish RCOR1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- RCOR1 Related Articles
RCOR1 involved in several pathways and played different roles in them. We selected most pathways RCOR1 participated on our site, such as Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with RCOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | DNALI1;TBPL2;UQCRC1;HAP1;NDUFS4;TBP;SDHD;VDAC1;ATP5C1 |
RCOR1 has several biochemical functions, for example, DNA binding, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RCOR1 itself. We selected most functions RCOR1 had, and list some proteins which have the same functions with RCOR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | HIST3H2A;E4F1;ZNF70;IFIH1;HMGA1A;NFRKB;KMT2A;SOX19A;TBX3A |
| enzyme binding | ZFP36;PTPLA;DYM;MLEC;NOXO1;MST1R;HSPA2;RCOR2;MARCH6 |
| protein binding | NME3;RAD23B;FBXO25;IRF1;HBXIP;NSG1;NF1;GPM6A;DUSP7 |
| transcription regulatory region DNA binding | ZFP161;BASP1;IKZF4;GFI1;TCF7L2;MTERFD3;SNCA;IKZF3;PRDM5 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | REST;CC2D1B;CUX2;PROX1;NKX6-1;HINFP;BCL11A;YY1;PPARA |
RCOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RCOR1.
Nr4a2; Gfi1b; inos_mouse_gene; tnfa_mouse_gene; Hdac1; Hdac2; Nanog
- Q&As
- Reviews
Q&As (5)
Ask a questionPotential limitations include the need for standardized assays, variability in protein expression levels, and the influence of confounding factors on its levels.
Yes, genetic variations in the RCOR1 gene have been associated with susceptibility to certain neurodegenerative and neurodevelopmental disorders.
Dysregulation of RCOR1 protein has been associated with neurodevelopmental disorders such as autism spectrum disorders and intellectual disabilities.
RCOR1 protein interacts with various transcription factors and epigenetic regulators, and understanding these interactions is crucial for its clinical relevance.
There is emerging research into using RCOR1 protein profiles for personalized treatment strategies in neurology, especially for patients with neurodegenerative and neurodevelopmental conditions.
Customer Reviews (3)
Write a reviewSuch dedicated support makes me feel confident in my choice of using the RCOR1 protein for my experiments.
I am highly impressed with the RCOR1 protein as it is of exceptionally high quality, and I am confident that it will perfectly meet the specific requirements of my experiments.
With their extensive knowledge and expertise, I am assured that any challenges or issues I may encounter during my research will be efficiently resolved.
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