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RHOG

Official Full Name

ras homolog gene family, member G (rho G)
Overview

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X.
Synonyms

RHOG; ras homolog gene family, member G (rho G); ARHG; rho-related GTP-binding protein RhoG; MGC125835; MGC125836; Rho related GTP binding protein RhoG precursor; RHOG_HUMAN;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

E. coli
E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RHOG-6843H	Recombinant Human Ras Homolog Family Member G, His-tagged	E.coli	His	1-188aa	Inquiry
Human	RHOG-30980TH	Recombinant Human RHOG, His-tagged	E.coli	His		Inquiry
Human	RHOG-542HCL	Recombinant Human RHOG lysate	HEK293	N/A		Inquiry
Human	RHOG-683H	Recombinant Human RHOG protein, His-tagged	E. coli	His	74-191 aa	Inquiry
Mouse	RHOG-14175M	Recombinant Mouse RHOG Protein	Mammalian Cell	His		Inquiry
Mouse	RHOG-7590M-B	Recombinant Mouse RHOG Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	RHOG-7590M	Recombinant Mouse RHOG Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	RHOG-3888R	Recombinant Rhesus monkey RHOG Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	RHOG-3705R-B	Recombinant Rhesus Macaque RHOG Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	RHOG-3705R	Recombinant Rhesus Macaque RHOG Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	RHOG-1910C	Recombinant Chicken RHOG	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RHOG Related Articles

RHOG involved in several pathways and played different roles in them. We selected most pathways RHOG participated on our site, such as Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Bacterial invasion of epithelial cells	PIK3R1;MAD2L2;CAV1;CRKL;VCL;DOCK1;CD2AP;SHC1;CBL
Shigellosis	RHOG;U2AF1L4;MAPK11;RIPK2;MAPK12;CD44;MAPK13;ITGB1;PFN3
Salmonella infection	CASP1;WASLA;MAPK8B;DYNC1LI2;CCL3;RHOGD;TLR4;CASPA;RELA

RHOG has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOG itself. We selected most functions RHOG had, and list some proteins which have the same functions with RHOG. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	RRAS;GNAO1;RHOGD;RAP2B;RASD1;ARL4CA;ARL8BA;LANCL2;PPP1CA
GTPase activity	GNAL;GTPBP4;TUBB4A;GBP2;GTPBP10;RAB5AB;RAB28;LRRK2;TUBB6
protein binding	TMED5;GATAD2B;AP5Z1;CD72;GNGT1;ZUFSP;PRPS2;SMN1;PHF19

RHOG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOG here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOG.

ELMO1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; ATP6AP2; RAB7A; DOCK1; Coro1c

Samson, T; van Buul, JD; et al. The Guanine-Nucleotide Exchange Factor SGEF Plays a Crucial Role in the Formation of Atherosclerosis. PLOS ONE 8:-(2013).

Faugaret, D; Chouinard, FC; et al. An essential role for phospholipase D in the recruitment of vesicle amine transport protein-1 to membranes in human neutrophils. BIOCHEMICAL PHARMACOLOGY 81:144-156(2011).