RHOT1
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Official Full Name
ras homolog gene family, member T1
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Overview
Mitochondrial Rho GTPase 1 is an enzyme that in humans is encoded by the RHOT1 gene. -
Synonyms
RHOT1; ras homolog gene family, member T1; ARHT1; mitochondrial Rho GTPase 1; FLJ11040; MIRO 1; ARHT 1; FLJ12633; hMiro 1; hMiro1; MIRO1; Mitochondrial Rho 1; Mitochondrial Rho1; Rac GTP binding protein like protein; Ras homolog gene family member T1; Rhot 1; hMiro-1; rac-GTP binding protein-like protein; rac-GTP-binding protein-like protein; MIRO-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|SUMO
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | RHOT1-261H | Active Recombinant Human RHOT1 protein, His-tagged | E.coli | His |
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| Human | RHOT1-1506HCL | Recombinant Human RHOT1 cell lysate | N/A |
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| Mouse | RHOT1-14178M | Recombinant Mouse RHOT1 Protein | Mammalian Cell | His |
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| Mouse | RHOT1-7592M-B | Recombinant Mouse RHOT1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | RHOT1-7592M | Recombinant Mouse RHOT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Chicken | RHOT1-1357C | Recombinant Chicken RHOT1 | Mammalian Cell | His |
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| Chicken | RHOT1-2027C | Recombinant Chicken RHOT1 Protein (1-219 aa), His-SUMO-tagged | E.coli | His/SUMO | 1-219 aa |
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- Involved Pathway
- Protein Function
- Interacting Protein
- RHOT1 Related Articles
- RHOT1 Related Research Area
RHOT1 involved in several pathways and played different roles in them. We selected most pathways RHOT1 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rho GTPase cycle | STARD8;ARHGAP11A;ABR;ARHGAP36;CHN2;ARHGAP1;RHOT1;RHOT1A;RHOT1B |
| Signal Transduction | RBP3;PMEPA1;LRP12;FABP11B;TAAR1;CRABP1A;PPEF1;PDK2B;ANXA1B |
| Signaling by Rho GTPases | PRC1B;ARHGAP22;ARHGAP23;IQGAP3;ARHGAP6;RHOT1;PRC1;GDI2;ARHGAP17B |
RHOT1 has several biochemical functions, for example, GTP binding, GTPase activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOT1 itself. We selected most functions RHOT1 had, and list some proteins which have the same functions with RHOT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | PCK1;RAB25;RAB33A;GUCY2E;RAB40AL;RAB28;RAB7A;ATL2;RALBA |
| GTPase activity | ARF4;TUBD1;GNA15;ARF5;RAB17;EEF1A1;RAB8B;RAC2;RHOQ |
| calcium ion binding | MMP1A;CRB1;CLEC3B;TPD52;CAPNS1A;DNASE1L3;PLA2G2E;CANT1A;CDH13 |
| molecular_function | EEF2KMT;TMEM51;ZNF24;TGTP2;TMED1B;FAM19A4B;ASXL3;CRYGMXL2;HIST1H4G |
| protein binding | RHOH;VPS4B;ZFPM1;ROPN1B;INO80E;FBXO17;SEC31A;ZNF670;VMP1 |
RHOT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOT1.
TRAK1; Kif5c; PARK2; KIF5C; PINK1; Trak2
- Q&As
- Reviews
Q&As (5)
Ask a questionResearchers are exploring the development of small molecule inhibitors or activators targeting RHOT1 protein for potential clinical applications in the future.
Dysregulation of RHOT1 protein has been implicated in neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
Yes, mutations in the RHOT1 gene can disrupt mitochondrial dynamics and lead to mitochondrial dysfunction, which may contribute to the development of various diseases.
RHOT1 protein is involved in the maintenance of mitochondrial morphology, regulation of mitochondrial fission and fusion, and control of mitochondrial dynamics.
RHOT1 protein and its associated pathways are being investigated as potential therapeutic targets for neurodegenerative diseases and other disorders characterized by mitochondrial dysfunction.
Customer Reviews (3)
Write a reviewThis versatility allows me to explore different aspects of my research with confidence and accuracy.
the RHOT1 protein's excellent functionality makes it highly suitable for various trial applications.
Whether I am investigating enzymatic activity, studying protein-protein interactions, or testing its role in signaling pathways, the RHOT1 protein consistently performs exceptionally well.
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