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RNASE2

Official Full Name

ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
Overview

Non-secretory ribonuclease is an enzyme that in humans is encoded by the RNASE2 gene.
Synonyms

RNASE2; ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin); RNS2; non-secretory ribonuclease; EDN; Ear4; EC=3.1.27.5; Eosinophil cationic type ribonuclease 4; MR 4; Non secretory ribonuclease; R14; R15; R5; Ribonuclease 2; Ribonuclease RNase A family 2 (liver eosinophil derived neurotoxin); Ribonuclease US; RNase 2; RNase UpI 2; RNase UpI-2; eosinophil-derived neurotoxin;

Type

Cell & Tissue Lysates
Recombinant Proteins
Native Proteins

Species

Human
Rat

Source

E.coli
Human Neutrophil
In Vitro Cell Free System
Protein Conjugation
Sf9, Baculovirus cells
Wheat Germ

Tag

GST
His
N/A
N
SUMO

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RNASE2-1514HCL	Recombinant Human RNASE2 cell lysate		N/A		Inquiry
Human	RNASE2-2832H	Recombinant Human RNASE2 Protein, His-tagged, OVA Conjugated	Protein Conjugation	N-His	Arg124-Val152	Inquiry
Human	RNASE2-171H	Native Human Eosinophil Derived Neurotoxin	Human Neutrophil	N/A		Inquiry
Human	RNASE2-779H	Recombinant Human RNASE2 Protein (28-161 aa), His-tagged	E.coli	His	28-161 aa	Inquiry
Human	RNASE2-1210H	Recombinant Human RNASE2 Protein, His&SUMO-tagged	E.coli	N-His&SUMO	Lys28-Ile161	Inquiry
Human	RNASE2-01H	Recombinant Human RNASE2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	RNASE2-02H	Recombinant Human RNASE2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	RNASE2-03H	Recombinant Human RNASE2 protein, His-tagged	Sf9, Baculovirus cells	His	143aa	Inquiry
Human	RNASE2-6875HF	Recombinant Full Length Human RNASE2 Protein, GST-tagged	In Vitro Cell Free System	GST	161 amino acids	Inquiry
Rat	Rnase2-2020R	Recombinant Rat Rnase2 Protein, His-tagged	E.coli	N-His	Gln26-Phe155	Inquiry

Involved Pathway
Protein Function
Interacting Protein
RNASE2 Related Articles

RNASE2 involved in several pathways and played different roles in them. We selected most pathways RNASE2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RNASE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RNASE2 has several biochemical functions, for example, endonuclease activity, nucleic acid binding, ribonuclease A activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNASE2 itself. We selected most functions RNASE2 had, and list some proteins which have the same functions with RNASE2. You can find most of the proteins on our site.

Function	Related Protein
endonuclease activity	RNASEL2;CL2;EAR5;DROSHA;RNASEL4;DCLRE1C;PELO;EAR3;CENPT
nucleic acid binding	ZFP422;EAR5;AEN;ZFP184;ZBTB10;GPATCH2;TDRD12;ZFP770;NELFE
ribonuclease A activity	EAR4;RNASE2;RNASE4;EAR5;RNASE1
ribonuclease activity	EAR3;ANG3;RNASEL4;RNASE7;RNASET2B;RNASE3;ANG;EAR2;EAR1

RNASE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNASE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNASE2.

Rosenberg, HF; et al. Eosinophil-derived neurotoxin/RNase 2: Connecting the past, the present and the future. CURRENT PHARMACEUTICAL BIOTECHNOLOGY 9:135-140(2008).

Nitto, T; Dyer, KD; et al. Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo. GENES AND IMMUNITY 5:668-674(2004).