RPS6KB2 Protein


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Official Full Name ribosomal protein S6 kinase, 70kDa, polypeptide 2
Background This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Synonyms RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase beta-2; KLS; P70 BETA; p70S6Kb; STK14B; P70S6K2; S6K-beta; p70 S6KB; p70-S6K 2; S6K-beta-2; p70 S6K-beta; p70 S6 kina
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Rabbit
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • MBP
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPS6KB2-5193H Recombinant Human RPS6KB2 protein, GST-tagged E.coli GST
    Human CPBT-Y0065RH Rabbit Anti-Human p70 S6 Kinase (S6K) Polyclonal Antibody Rabbit N/A
    Human RPS6KB2-1935H Recombinant Human RPS6KB2 protein, His & GST-tagged E.coli His/GST
    Human RPS6KB2-2158HCL Recombinant Human RPS6KB2 293 Cell Lysate HEK293 N/A
    Human RPS6KB2-2437H Recombinant Human RPS6KB2, His-tagged E.coli His
    Human RPS6KB2-30578TH Recombinant Human RPS6KB2 N/A
    Human RPS6KB2-30618TH Recombinant Human RPS6KB2 N/A
    Human RPS6KB2-3112H Recombinant Human RPS6KB2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human RPS6KB2-360H Recombinant Human RPS6KB2 protein, His/MBP-tagged E.coli His/MBP
    Human RPS6KB2-377H Recombinant Human RPS6KB2, GST-tagged, Active Sf9 Insect Cell GST
    Mouse RPS6KB2-14500M Recombinant Mouse RPS6KB2 Protein Mammalian Cell His
    Mouse Rps6kb2-5614M Recombinant Mouse Rps6kb2 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    RPS6KB2 involved in several pathways and played different roles in them. We selected most pathways RPS6KB2 participated on our site, such as ErbB signaling pathway, HIF- signaling pathway, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway HRASB; NCK2B; HBEGFB; MAP2K4; PAK7; MAPK8; PAK6B; CBLC; HBEGFA; NCK2A
    HIF- signaling pathway PIK3CA; NOS3; SLC2A1; NOS2; GM5506; VEGFA; NFKB1; VHL; PIK3CB; Il6ra
    mTOR signaling pathway RPTOR; AKT1; RPS6KB1B; PTENA; RPS6; RRAGCA; AKT1S1; RHEB; TSC1; STK11
    PIK-Akt signaling pathway MAP2K1; PIK3CA; MCL1; IL2RA; ITGB8; PTEN; TCL1B4; GNG4; FOXO3; FGF17
    AMPK signaling pathway RPS6KB1; ADIPOR2; PFKL; INSR; RAB8A; CCNA1; INS1; PRKAA2; ACACA; PPP2R5C
    TGF-beta signaling pathway ZFYVE16; ID2; SMAD7B; TFDP1; SMAD7; ROCK2B; BMPR2B; TGFB3; BMP4; BMP2B
    Fc gamma R-mediated phagocytosis MAPK3; BIN1; FCGR1; FCGR2B; PPAP2B; ARPC1A; LAT; MARCKSL1; PRKCB; WASL
    Insulin signaling pathway PPP1CBL; PDPK1B; MKNK2A; PRKAA1; PTPN1; PCK1; IKBKB; MAPK3; EIF4E1C; SOCS9
    Insulin resistance PPP1R3D; GSK3AA; RPS6KA6; SLC2A2; SLC27A1A; PRKAB1; NFKBIAB; NFKB1; PIK3R5; RPS6KA3
    Proteoglycans in cancer ANK2; HRAS; CAMK2G; GPC1; WNT2B; CBLB; MAP2K1; WNT6; NRAS; FZD5
    Acute myeloid leukemia AKT1; FLT3; AKT2; RUNX1; ZBTB16; MAP2K2; MYC; GRB2; STAT5A; SPI1
    Choline metabolism in cancer PRKCA; HIF1A; PIP5K1C; SLC5A7; PIK3R1; WAS; RAC3; PLD1; PIK3CA; PIK3R3

    RPS6KB2 has several biochemical functions, for example, ATP binding, peptide binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KB2 itself. We selected most functions RPS6KB2 had, and list some proteins which have the same functions with RPS6KB2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PFTK1; ABCB1A; TAE1; MYLK2; PLK3; DDX3X; ULK4; ADCY1; P2RX3B; MYO3B
    peptide binding RNPEP; LNPEP; GPR22; NPFFR1; NPFFR1L3; IDE; HCRTR2; ERCC3; RNPEPL1; NPFFR2
    protein kinase activity STK25; BMPR1BA; CSNK1DB; PTK2AB; IGF1RA; JAK2A; CDK5; AURKA; ACVR1L; TBRG4
    protein serine/threonine kinase activity STK31; ACVR1BA; SIK3; STK32C; STK32A; CPNE3; BMPR1BB; SMG1; MAP2K2; ROCK1
    ribosomal protein S6 kinase activity RPS6KB1B; RPS6KA6; ALPK2; RPS6KA3B; RPS6KB1; RPS6KA3A; RPS6KA1; RPS6KA4; RPS6KA2; RPS6KA3

    RPS6KB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KB2.


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