Recombinant Human RPS6KB2 protein, His & GST-tagged

• Cat.No.: RPS6KB2-1935H
• Product Overview: Recombinant Human RPS6KB2 aa. (Asp194~Pro453 (Accession # Q9UBS0)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Asp194~Pro453
• Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 61.6kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 6.6

Gene Information

• Gene Name: RPS6KB2 ribosomal protein S6 kinase B2 [ Homo sapiens (human) ]
• Official Symbol: RPS6KB2
• Synonyms: RPS6KB2; ribosomal protein S6 kinase B2; KLS; SRK; S6K2; STK14B; p70S6Kb; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta; ribosomal protein S6 kinase beta-2; 70 kDa ribosomal protein S6 kinase 2; P70S6K2; S6 kinase-related kinase; S6K-beta; S6K-beta-2; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70 ribosomal S6 kinase beta; p70-S6K 2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; serine/threonine-protein kinase 14 beta; serine/threonine-protein kinase 14B
• Gene ID: 6199
• mRNA Refseq: NM_003952.2
• Protein Refseq: NP_003943.2
• UniProt ID: Q9UBS0