Human RPS6KB2 Knockdown Cell Lysate

• Cat.No.: RPS6KB2-422HKCL
• Product Overview: WB-validated RPS6KB2 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 53 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg RPS6KB2 KD HeLa cell lysate
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [ Homo sapiens (human) ]
• Official Symbol: RPS6KB2
• Synonyms: RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase beta-2; KLS; P70 BETA; p70S6Kb; STK14B; P70S6K2; S6K-beta; p70 S6KB; p70-S6K 2; S6K-beta-2; p70 S6K-beta; p70 S6 kinase beta; S6 kinase-related kinase; p70 ribosomal S6 kinase beta; serine/threonine-protein kinase 14B; 70 kDa ribosomal protein S6 kinase 2; serine/threonine-protein kinase 14 beta; SRK; S6K2; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta
• Gene ID: 6199
• mRNA Refseq: NM_003952
• Protein Refseq: NP_003943
• MIM: 608939
• UniProt ID: Q9UBS0