S100A4 Protein


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Official Full Name S100 calcium binding protein A4
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Synonyms S100A4; S100 calcium binding protein A4; 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98; protein S100-A4; protein Mts1; fibroblast-specific protein-1; placental calcium-binding protein; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog);
    • Species :
    • Cattle
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • Tag :
    • C-Myc/DDK
    • Fc
    • Flag
    • GST
    • hFc
    • His
    • His (Fc)-Avi
    • Myc
    • His-SUMO
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human S100A4-162H Recombinant Human S100A4 Mammalian Cell His Inquiry
    Human S100A4-195H Recombinant Human S100A4 Protein, His-tagged E.coli His Inquiry
    Human S100A4-201H Recombinant Human S100 Calcium Binding Protein A4 E.coli N/A Inquiry
    Human S100A4-2489H Recombinant Human S100A4, GST-tagged E.coli GST Inquiry
    Human S100A4-31367TH Recombinant Human S100A4 E.coli N/A Inquiry
    Human S100A4-3727H Recombinant Human S100A4, His-tagged E.coli His Inquiry
    Human S100A4-409H Recombinant Human S100 Calcium Bbinding Protein A4, His-tagged E.coli His Inquiry
    Human S100A4-70H Recombinant Human S100A4, Fc tagged Human Cell Fc
    Human S100A4-89H Recombinant Human S100A4 E.coli N/A Inquiry
    Mouse S100A4-159M Recombinant Mouse S100a4, Fc tagged Human Cell His Inquiry
    Mouse S100a4-3542M Recombinant Mouse S100a4, His-tagged E.coli His Inquiry
    Mouse S100a4-5105M Recombinant Mouse S100 calcium Binding Protein A4, His-tagged Mouse His Inquiry
    Mouse S100a4-532M Recombinant Mouse S100a4 Human Cell N/A Inquiry
    Mouse S100a4-533M Recombinant Mouse S100a4, His-tagged E.coli His Inquiry
    Rat S100A4-5213R Recombinant Rat S100A4 Protein Mammalian Cell His Inquiry
    Cattle S100A4-2120C Recombinant Cattle S100A4 protein, His-tagged E.coli His Inquiry
    Human S100A4-2859HCL Recombinant Human S100A4 cell lysate Human Cell N/A Inquiry
    Mouse S100A4-001MCL Recombinant Mouse S100A4 cell lysate Human Cell N/A Inquiry
    Human S100A4-1051HFL Recombinant Full Length Human S100A4 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Human S100A4-1940H Recombinant Human S100A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human S100A4-3461H Recombinant Human S100A4 protein, His-SUMO-tagged E.coli His-SUMO Inquiry
    Human S100A4-4022H Recombinant Human S100A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Rat S100A4-4872R Recombinant Rat S100A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Mouse S100a4-566M Recombinant Mouse S100a4 Protein, hFc-tagged HEK293 hFc Inquiry
    Human S100A4-385H Recombinant Human S100A4 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK Inquiry
    Human S100A4-4590H Recombinant Human S100A4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse S100a4-5669M Recombinant Mouse S100a4 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry
    Mouse S100a4-7323M Recombinant Mouse S100a4 Protein, His-tagged E.coli His Inquiry
    Rat S100A4-2599R Recombinant Rat S100A4 Protein (2-101 aa), His-Myc-tagged E.coli His/Myc Inquiry

    S100A4 involved in several pathways and played different roles in them. We selected most pathways S100A4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    S100A4 has several biochemical functions, for example, RAGE receptor binding, actin binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A4 itself. We selected most functions S100A4 had, and list some proteins which have the same functions with S100A4. You can find most of the proteins on our site.

    Function Related Protein
    RAGE receptor binding S100A13; S100A4; S100A7; S100A8; HMGB1; S100A9; FPR1; HMGB2; S100B; S100P
    actin binding WIPF1; MSRB1; NEXN; AFAP1; SPTAN1; EZRB; CNN1; FSCN2B; MKL1B; HCLS1
    calcium ion binding CHP2; CALM4; TBC1D9B; F2; NINL; CA; AOC3; CABP7; CANT1B; CAPN1
    calcium-dependent protein binding C9orf9; SYT8; ANXA3; SYT1; DDX5; S100P; RBM22; STX1A; CALM1; SYN1
    identical protein binding RCAN1; PON2; PCBD1; LRRK2; APP; PLIN5; UBQLN1; CLDN16; CALCA; TLR3
    poly(A) RNA binding BZW1; PRPF4B; TPR; RPS27L; MTO1; TNS1; PSIP1; RBM47; DYNC1H1; U2SURP

    S100A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A4.

    TP53; S100B; MDM2; AREGB; BTC

    Grum-Schwensen, B; Klingelhofer, J; et al. S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance. BMC CANCER 15:-(2015).
    Wang, DG; Zhang, JW; et al. Functional expression, characterization and application of the human S100A4 protein. MOLECULAR MEDICINE REPORTS 11:175-181(2015).

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