S100A4 involved in several pathways and played different roles in them. We selected most pathways S100A4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
S100A4 has several biochemical functions, for example, RAGE receptor binding, actin binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A4 itself. We selected most functions S100A4 had, and list some proteins which have the same functions with S100A4. You can find most of the proteins on our site.
| Function |
Related Protein |
| RAGE receptor binding |
S100A13; S100A4; S100A7; S100A8; HMGB1; S100A9; FPR1; HMGB2; S100B; S100P |
| actin binding |
WIPF1; MSRB1; NEXN; AFAP1; SPTAN1; EZRB; CNN1; FSCN2B; MKL1B; HCLS1 |
| calcium ion binding |
CHP2; CALM4; TBC1D9B; F2; NINL; CA; AOC3; CABP7; CANT1B; CAPN1 |
| calcium-dependent protein binding |
C9orf9; SYT8; ANXA3; SYT1; DDX5; S100P; RBM22; STX1A; CALM1; SYN1 |
| identical protein binding |
RCAN1; PON2; PCBD1; LRRK2; APP; PLIN5; UBQLN1; CLDN16; CALCA; TLR3 |
| poly(A) RNA binding |
BZW1; PRPF4B; TPR; RPS27L; MTO1; TNS1; PSIP1; RBM47; DYNC1H1; U2SURP |
| protein binding |
SALL2; PHOSPHO2; EPM2A; SERPINE1; TUBA3D; GFM2; JOSD1; SERPINB5; C1QA; ALDOA |
S100A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A4.
TP53; S100B; MDM2; AREGB; BTC
Grum-Schwensen, B; Klingelhofer, J; et al. S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance. BMC CANCER 15:-(2015).
Wang, DG; Zhang, JW; et al. Functional expression, characterization and application of the human S100A4 protein. MOLECULAR MEDICINE REPORTS 11:175-181(2015).
