Recombinant Human S100A4
|Product Overview :
|Recombinant Human S100A4 was expressed in E. coli and purified using Glutathione sepharose affinity .
- Gene Information
- Related Products
|Cat. No. :
|S100 proteins belong to the family of calcium binding proteins such as Calmodulin and Troponin C. Members of the S100 protein family are multifunctional proteins implicated in the regulation of a variety of cellular activities and have both intracellular and extracellular activities. S100 proteins have no enzymatic activity and interact with several effector proteins within cells to regulate enzyme activities, dynamics of cytoskeleton constituents, cell growth and differentiation and Ca2+ homeostasis. S100 alpha is composed of an alpha and beta chain whereas S100 beta is composed of two beta chains. S100 protein is also expressed in antigen presenting cells such as Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
|Predicted MolecularMass :
|Liquid. In TRIS-acetate, pH 7.5, containing 1mM EDTA and 20% glycerol. No BSA or sodium azide.
|Long Term Storage :
|Gene Name :
|S100A4 S100 calcium binding protein A4 [ Homo sapiens ]
|S100A4; 18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98; Metastasin; S100 calcium-binding protein A4; fibroblast-specific protein-1; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog); Calvasculin; OTTHUMP00000015467; OTTHUMP00000015468; OTTHUMP00000015469; OTTHUMP00000032895; Placental calcium-binding protein; Protein Mts1; S100 calcium binding protein A4; S100 calcium-binding protein A4 (calcium protein,calvasculin, metastasin, murine placental homolog).
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|Chromosome Location :
|calcium ion binding, identical protein binding
|◆ Recombinant Protein
|Recombinant Human S100A4 Protein, His (Fc)-Avi-tagged
|Recombinant Human S100A4 Protein, MYC/DDK-tagged, C13 and N15-labeled
|Recombinant Mouse S100a4 Protein, Myc/DDK-tagged
|Recombinant Rat S100A4 Protein (2-101 aa), His-Myc-tagged
|Recombinant Rat S100A4 Protein, His (Fc)-Avi-tagged
|Recombinant Mouse S100A4 cell lysate
|Recombinant Human S100A4 cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
Drug development for S100A4 is currently in clinical trials, including small molecule inhibitors against S100A4 and inhibitors against the S100A4 signaling pathway.
Yes, the expression of S100A4 is affected by environmental factors, such as nutritional status, inflammation level, etc.
S100A4 plays an important role in tumor immunotherapy, it can act as a tumor-associated antigen, activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.
There is no conclusive evidence that diet improves the nutritional status of S100A4 protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.
In clinical practice, the expression level of S100A4 can be detected to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of oncological diseases.
Studies have shown that S100A4 protein can inhibit the occurrence of muscle wasting, but the specific mechanism is not clear.
Customer Reviews (3)Write a review
I have been using these for several years and they have been very stable and I swear by this product.
The experimental process is simple and there is no special environmental requirement.
It can remain stable under different temperature and pH conditions.
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