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Recombinant Human S100A4

Cat.No. : S100A4-31367TH
Product Overview : Recombinant full length human S100A4, 101 amino acids, 12kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source : E. coli
Tissue specificity : Ubiquitously expressed.
Biological activity : S100A4-31367TH is S100A4 antibody reactive.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5BSA and Azide free
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the S-100 family.Contains 2 EF-hand domains.
Gene Name : S100A4 S100 calcium binding protein A4 [ Homo sapiens ]
Official Symbol : S100A4
Synonyms : S100A4; S100 calcium binding protein A4; CAPL, MTS1, S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homol
Gene ID : 6275
mRNA Refseq : NM_002961
Protein Refseq : NP_002952
MIM : 114210
Uniprot ID : P26447
Chromosome Location : 1q12-q22
Function : RAGE receptor binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the current progress in drug development for S100A4? 04/28/2022

Drug development for S100A4 is currently in clinical trials, including small molecule inhibitors against S100A4 and inhibitors against the S100A4 signaling pathway.

Is the expression of S100A4 affected by environmental factors? 11/08/2021

Yes, the expression of S100A4 is affected by environmental factors, such as nutritional status, inflammation level, etc.

What role does S100A4 play in tumor immunotherapy? 08/10/2021

S100A4 plays an important role in tumor immunotherapy, it can act as a tumor-associated antigen, activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

How to improve the nutritional status of S100A4 protein through diet? 02/19/2021

There is no conclusive evidence that diet improves the nutritional status of S100A4 protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.

How can S100A4 be used as a biomarker in clinical practice? 01/22/2020

In clinical practice, the expression level of S100A4 can be detected to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of oncological diseases.

What is the relationship between S100A4 protein and muscle wasting? 12/31/2019

Studies have shown that S100A4 protein can inhibit the occurrence of muscle wasting, but the specific mechanism is not clear.

Customer Reviews (3)

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Reviews
10/07/2022

    I have been using these for several years and they have been very stable and I swear by this product.

    04/14/2022

      The experimental process is simple and there is no special environmental requirement.

      11/20/2021

        It can remain stable under different temperature and pH conditions.

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