Recombinant Human S100A4
Cat.No. : | S100A4-31367TH |
Product Overview : | Recombinant full length human S100A4, 101 amino acids, 12kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Source : | E. coli |
Tissue specificity : | Ubiquitously expressed. |
Biological activity : | S100A4-31367TH is S100A4 antibody reactive. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5BSA and Azide free |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the S-100 family.Contains 2 EF-hand domains. |
Gene Name : | S100A4 S100 calcium binding protein A4 [ Homo sapiens ] |
Official Symbol : | S100A4 |
Synonyms : | S100A4; S100 calcium binding protein A4; CAPL, MTS1, S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) , S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homol |
Gene ID : | 6275 |
mRNA Refseq : | NM_002961 |
Protein Refseq : | NP_002952 |
MIM : | 114210 |
Uniprot ID : | P26447 |
Chromosome Location : | 1q12-q22 |
Function : | RAGE receptor binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
S100a4-5669M | Recombinant Mouse S100a4 Protein, Myc/DDK-tagged | +Inquiry |
S100A4-2599R | Recombinant Rat S100A4 Protein (2-101 aa), His-Myc-tagged | +Inquiry |
S100A4-1940H | Recombinant Human S100A4 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A4-4872R | Recombinant Rat S100A4 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A4-385H | Recombinant Human S100A4 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
S100A4-001MCL | Recombinant Mouse S100A4 cell lysate | +Inquiry |
S100A4-2859HCL | Recombinant Human S100A4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionDrug development for S100A4 is currently in clinical trials, including small molecule inhibitors against S100A4 and inhibitors against the S100A4 signaling pathway.
Yes, the expression of S100A4 is affected by environmental factors, such as nutritional status, inflammation level, etc.
S100A4 plays an important role in tumor immunotherapy, it can act as a tumor-associated antigen, activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.
There is no conclusive evidence that diet improves the nutritional status of S100A4 protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.
In clinical practice, the expression level of S100A4 can be detected to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of oncological diseases.
Studies have shown that S100A4 protein can inhibit the occurrence of muscle wasting, but the specific mechanism is not clear.
Customer Reviews (3)
Write a reviewI have been using these for several years and they have been very stable and I swear by this product.
The experimental process is simple and there is no special environmental requirement.
It can remain stable under different temperature and pH conditions.
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