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Official Full Name sialic acid binding Ig-like lectin 1, sialoadhesin
Background This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule;that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane;protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions.;Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound;;however, the full-length nature of this variant has not been determined.
Synonyms SIGLEC1; sialic acid binding Ig-like lectin 1, sialoadhesin; sialoadhesin , SN; sialoadhesin; CD169; dJ1009E24.1; FLJ00051; FLJ00055; FLJ00073; FLJ32150; SIGLEC 1; sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; SN; SIGLEC-1; FLJ00411; DKFZp667F058
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293T
    • Mammalian cells
    • Tag :
    • Fc Chimera
    • His
    • Myc/DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SIGLEC1-5677H Recombinant Human SIGLEC1 protein, His-tagged E.coli His
    Human SIGLEC1-838H Recombinant Human SIGLEC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Siglec1-523M Recombinant Mouse Siglec1, Fc Chimera Mammalian cells Fc Chimera
    Mouse Siglec1-5876M Recombinant Mouse Siglec1 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    SIGLEC1 involved in several pathways and played different roles in them. We selected most pathways SIGLEC1 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) NRCAM; CD58; CD276; CLDN5B; BLB1; OCLNB; CD226; Siglec1; ITGA6; GLG1

    SIGLEC1 has several biochemical functions, for example, carbohydrate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC1 itself. We selected most functions SIGLEC1 had, and list some proteins which have the same functions with SIGLEC1. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding NOMO3; CD302; GALNT11; CHODL; OS9; SFTPD; EMC7; CALR; SIGLEC6; BCAN
    protein binding SPACA3; HTR1A; POLI; CTAG1B; TSC22D4; TXNRD1; CAPNS1; MKI67IP; ACVR1L; ACTR3

    SIGLEC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC1.

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